{
  "id": 18101,
  "label": "tubulocystic renal cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017890",
  "properties": {
    "xrefs": [
      "GARD:0021419",
      "MEDGEN:925623",
      "NCIT:C126303",
      "Orphanet:319325",
      "SCTID:733603009",
      "UMLS:C4288091"
    ],
    "synonyms": [
      "Tubulocystic renal cell cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Tubulocystic renal cell carcinoma is an extremely rare subtype of renal cell carcinoma most frequently characterized by a small, solitary, well-circumscribed, unencapsulated renal tumor composed of multiple small to medium-sized cysts with a white or gray, spongy (\"bubble wrap-like\") cut surface. Patients are usually asymptomatic or could manifest with abdominal pain, abdominal distension and/or hematuria. Progression, recurrence and metastasis rarely occur although lymph node, bone, pleura and liver mestatsis have been reported."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7199,
      "label": "renal cell adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6814
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005708",
          "GARD:0024205",
          "ICDO:8311/1",
          "ICDO:8312/3",
          "NANDO:2200045",
          "NCIT:C9385"
        ],
        "synonyms": [
          "renal cell carcinoma",
          "RCC",
          "adenocarcinoma of kidney",
          "adenocarcinoma of the kidney",
          "carcinoma, renal cell, malignant",
          "kidney adenocarcinoma",
          "renal cell adenocarcinoma",
          "renal cell cancer",
          "renal cell carcinoma, stage unspecified"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma arising from the renal parenchyma. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy."
      },
      "child_count": 9,
      "reference_id": "MONDO:0005549"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7199,
      "label": "renal cell adenocarcinoma"
    }
  ]
}