{
  "id": 18105,
  "label": "familial papillary or follicular thyroid carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017895",
  "properties": {
    "xrefs": [
      "GARD:0008488",
      "MEDGEN:1681657",
      "NCIT:C118829",
      "Orphanet:319487",
      "UMLS:C5191836"
    ],
    "synonyms": [
      "FNMTC",
      "familial nonmedullary thyroid gland carcinoma",
      "familial pure nonmedullary thyroid carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A papillary or follicular thyroid gland carcinoma with a genetic component that develops within the same family. Current studies suggest that it is inherited in an autosomal dominant pattern. It is often multifocal and bilateral and usually affects younger patients."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 16290,
      "label": "differentiated thyroid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080525",
          "EFO:1002017",
          "GARD:0012027",
          "MEDGEN:277876",
          "NCIT:C7153",
          "ONCOTREE:WDTC",
          "Orphanet:146",
          "UMLS:C1337013"
        ],
        "synonyms": [
          "differentiated thyroid cancer",
          "differentiated thyroid carcinoma",
          "differentiated thyroid gland cancer",
          "differentiated thyroid gland carcinoma",
          "papillary or follicular thyroid carcinoma",
          "thyroid gland differentiated carcinoma",
          "thyroid gland well differentiated carcinoma",
          "well differentiated thyroid carcinoma",
          "well differentiated thyroid gland carcinoma",
          "well-differentiated thyroid cancer",
          "well-differentiated thyroid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Differentiated thyroid carcinoma (DTC), also known as papillary or follicular thyroid carcinoma, is a slow-growing malignancy usually presenting in adults as an asymptomatic thyroid mass."
      },
      "child_count": 3,
      "reference_id": "MONDO:0015447"
    },
    {
      "id": 18106,
      "label": "familial nonmedullary thyroid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        16049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021421",
          "MEDGEN:502247",
          "OMIMPS:188550",
          "Orphanet:319494",
          "UMLS:C3501843"
        ],
        "synonyms": [
          "thyroid cancer, nonmedullary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Familial nonmedullary thyroid carcinoma (fNMTC) is a rare non-syndromic form of thyroid cancer characterized by occurrence of thyroid carcinoma (TC) as the primary feature in a familial setting."
      },
      "child_count": 6,
      "reference_id": "MONDO:0017896"
    }
  ],
  "children": [
    {
      "id": 9853,
      "label": "thyroid cancer, nonmedullary, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6768,
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0005206",
          "MEDGEN:904175",
          "MESH:C572845",
          "OMIM:188470",
          "UMLS:C4225426"
        ],
        "synonyms": [
          "thyroid cancer, nonmedullary, 2",
          "thyroid cancer, nonmedullary, 2, autosomal dominant, somatic mutation",
          "thyroid cancer, nonmedullary, type 2",
          "thyroid carcinoma, follicular, autosomal dominant, somatic mutation",
          "thyroid carcinoma, follicular, somatic",
          "FTC",
          "NMTC2",
          "thyroid cancer, follicular",
          "thyroid carcinoma, follicular"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008566"
    },
    {
      "id": 12427,
      "label": "thyroid carcinoma, nonmedullary, with or without cell oxyphilia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015354",
          "MEDGEN:400409",
          "MESH:C537842",
          "OMIM:603386",
          "UMLS:C1863925"
        ],
        "synonyms": [
          "thyroid carcinoma, nonmedullary, with cell oxyphilia",
          "thyroid carcinoma, nonmedullary, with or without cell oxyphilia",
          "TCO",
          "TCO 1",
          "TCO1",
          "nonmedullary thyroid carcinoma, with or without cell oxyphilia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011312"
    },
    {
      "id": 12478,
      "label": "papillary thyroid Microcarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015358",
          "ICDO:8341/3",
          "MEDGEN:313563",
          "MESH:C563277",
          "NCIT:C46004",
          "OMIM:603744",
          "UMLS:C1709457"
        ],
        "synonyms": [
          "papillary Microcarcinoma of the thyroid",
          "papillary Microcarcinoma of the thyroid gland",
          "papillary thyroid Microcarcinoma",
          "papillary thyroid gland Microcarcinoma",
          "thyroid gland papillary Microcarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A papillary carcinoma of the thyroid gland measuring 10mm or less in diameter. The survival rates of patients with this type of carcinoma are the same with those of the normal population."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011368"
    },
    {
      "id": 12745,
      "label": "thyroid cancer, nonmedullary, 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015391",
          "MEDGEN:903332",
          "OMIM:606240",
          "UMLS:C4225410"
        ],
        "synonyms": [
          "NMTC3",
          "thyroid cancer, nonmedullary, 3",
          "thyroid carcinoma, nonmedullary, 3",
          "thyroid cancer, nonmedullary, 1",
          "thyroid cancer, nonmedullary, 1, formerly"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011653"
    },
    {
      "id": 15676,
      "label": "thyroid cancer, nonmedullary, 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6768,
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016132",
          "MEDGEN:907624",
          "OMIM:616534",
          "UMLS:C4225293"
        ],
        "synonyms": [
          "FOXE1 thyroid cancer, nonmedullary",
          "thyroid cancer, nonmedullary caused by mutation in FOXE1",
          "thyroid cancer, nonmedullary, 4",
          "thyroid cancer, nonmedullary, type 4",
          "NMTC4"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Any thyroid cancer, nonmedullary in which the cause of the disease is a mutation in the FOXE1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014681"
    },
    {
      "id": 15677,
      "label": "thyroid cancer, nonmedullary, 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6768,
        18105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016133",
          "MEDGEN:895900",
          "OMIM:616535",
          "UMLS:C4225292"
        ],
        "synonyms": [
          "HABP2 thyroid cancer, nonmedullary",
          "thyroid cancer, nonmedullary caused by mutation in HABP2",
          "thyroid cancer, nonmedullary, 5",
          "thyroid cancer, nonmedullary, type 5",
          "NMTC5"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Any thyroid cancer, nonmedullary in which the cause of the disease is a mutation in the HABP2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014682"
    }
  ],
  "roots": [
    {
      "id": 16290,
      "label": "differentiated thyroid carcinoma"
    },
    {
      "id": 18106,
      "label": "familial nonmedullary thyroid carcinoma"
    }
  ]
}