{
  "id": 18106,
  "label": "familial nonmedullary thyroid carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017896",
  "properties": {
    "xrefs": [
      "GARD:0021421",
      "MEDGEN:502247",
      "OMIMPS:188550",
      "Orphanet:319494",
      "UMLS:C3501843"
    ],
    "synonyms": [
      "thyroid cancer, nonmedullary"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Familial nonmedullary thyroid carcinoma (fNMTC) is a rare non-syndromic form of thyroid cancer characterized by occurrence of thyroid carcinoma (TC) as the primary feature in a familial setting."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 16049,
      "label": "thyroid gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4245,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3963",
          "EFO:0002892",
          "GARD:0019763",
          "HP:0002890",
          "MEDGEN:107811",
          "MedDRA:10007476",
          "NANDO:2200074",
          "NCIT:C4815",
          "Orphanet:100088",
          "SCTID:448216007",
          "UMLS:C0549473"
        ],
        "synonyms": [
          "cancer of the thyroid",
          "cancer of thyroid",
          "head and neck cancer, thyroid",
          "thyroid cancer",
          "thyroid gland cancer",
          "carcinoma of the thyroid",
          "carcinoma of the thyroid gland",
          "carcinoma of thyroid",
          "carcinoma of thyroid gland",
          "thyroid carcinoma",
          "thyroid gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma arising from the thyroid gland. It is usually an adenocarcinoma and includes the following main subtypes: follicular, papillary, medullary, poorly differentiated, and anaplastic."
      },
      "child_count": 22,
      "reference_id": "MONDO:0015075"
    }
  ],
  "children": [
    {
      "id": 9854,
      "label": "thyroid cancer, nonmedullary, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6803,
        18106,
        24245
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024632",
          "MEDGEN:1648293",
          "OMIM:188550",
          "UMLS:C4721429"
        ],
        "synonyms": [
          "thyroid cancer, nonmedullary, 1",
          "thyroid cancer, nonmedullary, type 1",
          "NMTC1",
          "familial nonmedullary thyroid cancer, papillary",
          "nonmedullary thyroid carcinoma, papillary",
          "papillary carcinoma of thyroid"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008567"
    },
    {
      "id": 12674,
      "label": "familial papillary thyroid carcinoma with renal papillary neoplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18106
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016853",
          "MEDGEN:381339",
          "MESH:C565310",
          "OMIM:605642",
          "Orphanet:97290",
          "SCTID:717734005",
          "UMLS:C1854104"
        ],
        "synonyms": [
          "PTC-RCC",
          "ptc-RCC",
          "Prn1",
          "Ptcprn",
          "thyroid carcinoma, papillary, with papillary renal neoplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Familial papillary thyroid carcinoma with renal papillary neoplasia (fPTC/PRN) is an extremely rare inherited tumor syndrome within the familial nonmedullary thyroid cancer group (fNMTC)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011578"
    },
    {
      "id": 18105,
      "label": "familial papillary or follicular thyroid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16290,
        18106
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008488",
          "MEDGEN:1681657",
          "NCIT:C118829",
          "Orphanet:319487",
          "UMLS:C5191836"
        ],
        "synonyms": [
          "FNMTC",
          "familial nonmedullary thyroid gland carcinoma",
          "familial pure nonmedullary thyroid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A papillary or follicular thyroid gland carcinoma with a genetic component that develops within the same family. Current studies suggest that it is inherited in an autosomal dominant pattern. It is often multifocal and bilateral and usually affects younger patients."
      },
      "child_count": 12,
      "reference_id": "MONDO:0017895"
    }
  ],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 16049,
      "label": "thyroid gland carcinoma"
    }
  ]
}