{
  "id": 18163,
  "label": "syringomyelia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017987",
  "properties": {
    "xrefs": [
      "DOID:327",
      "GARD:0007725",
      "MEDGEN:21449",
      "MESH:D013595",
      "MedDRA:10042928",
      "NANDO:1200506",
      "NANDO:1200507",
      "NCIT:C85179",
      "NORD:1755",
      "Orphanet:3280",
      "SCTID:111496009",
      "UMLS:C0039144",
      "icd11.foundation:1161887622"
    ],
    "synonyms": [
      "hydromyelia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Syringomyelia is characterized by cerebrospinal fluid (CSF)-filled cavities (syrinx) inside the spinal cord, either as a result of a known cause (secondary syringomyelia, SS) or, more rarely, due to an unknown cause (primary syringomyelia, PS)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4611,
      "label": "spinal cord disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:319",
          "EFO:0009488",
          "ICD9:336.8",
          "ICD9:336.9",
          "MEDGEN:11550",
          "MESH:D013118",
          "NCIT:C97110",
          "SCTID:48522003",
          "UMLS:C0037928"
        ],
        "synonyms": [
          "disease of spinal cord",
          "disease of the spinal cord",
          "disease or disorder of spinal cord",
          "disorder of spinal cord",
          "spinal cord disease",
          "spinal cord disease or disorder",
          "spinal cord disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the spinal cord."
      },
      "child_count": 10,
      "reference_id": "MONDO:0002545"
    }
  ],
  "children": [
    {
      "id": 19959,
      "label": "primary syringomyelia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18163
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019691",
          "MEDGEN:721465",
          "Orphanet:99856",
          "SCTID:371076006",
          "UMLS:C1299627",
          "icd11.foundation:257905685"
        ],
        "synonyms": [
          "congenital syringomyelia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0020508"
    },
    {
      "id": 19960,
      "label": "secondary syringomyelia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18163
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019692",
          "MEDGEN:1649806",
          "Orphanet:99857",
          "UMLS:C4749399"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Secondary syringomyelia is a rare medullar disease defined as a development of a fluid-filled cavity or syrinx within the spinal cord due to blockage of CSF circulation (e.g., due to basal archnoiditis, meningeal carcinomatosis, various mass lesions), spinal cord injury (e.g., due to trauma, radiation necrosis, hemorrhage, spinal abscess), spinal dysraphism or intramedullary tumors. It presents with neuropathic pain, numbness, muscular weakness, changes in tone or spasticity or autonomic changes (hyperhidrosis, heart rate or blood pressure instability). Selective loss of pain and temperature with relative preservation of dorsal column function (touch and pressure) are classic findings."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020509"
    }
  ],
  "roots": [
    {
      "id": 4611,
      "label": "spinal cord disorder"
    }
  ]
}