{
  "id": 18203,
  "label": "congenital factor XIII deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018029",
  "properties": {
    "xrefs": [
      "DOID:2211",
      "GARD:0010766",
      "ICD9:286.3",
      "MEDGEN:4639",
      "NANDO:2200681",
      "NCIT:C131633",
      "Orphanet:331",
      "SCTID:50189006",
      "UMLS:C0015530"
    ],
    "synonyms": [
      "fibrin-stabilizing factor deficiency",
      "factor XIII deficiency",
      "fibrin stabilising factor deficiency",
      "fibrin stabilizing factor deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Congenital factor XIII deficiency is an inherited bleeding disorder due to reduced levels and activity of factor XIII (FXIII) and characterized by hemorrhagic diathesis frequently associated with spontaneous abortions and defective wound healing. Factor XIII deficiency is one of the most rare coagulation factor deficiencies."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4358,
      "label": "factor XIII deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0023095",
          "MEDGEN:1385982",
          "MESH:D005177",
          "NANDO:2200681",
          "UMLS:C4316906"
        ],
        "synonyms": [
          "FXIIID"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An acquired or inherited coagulation disorder due to reduced levels and activity of factor XIII."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002241"
    },
    {
      "id": 4360,
      "label": "hemorrhagic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2213",
          "ICD9:287.9",
          "MEDGEN:6799",
          "MESH:D006474",
          "NCIT:C115221",
          "UMLS:C0019087"
        ],
        "synonyms": [
          "bleeding diathesis",
          "bleeding disorder",
          "bleeding predisposition",
          "bleeding tendency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels (hemostatic disorders)."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002243"
    },
    {
      "id": 10564,
      "label": "congenital hematological disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:760584",
          "NCIT:C104003",
          "UMLS:C3267032"
        ],
        "synonyms": [
          "congenital haematological system disease",
          "congenital hematological disorder",
          "congenital hematological system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disorder of the blood that is present at birth."
      },
      "child_count": 21,
      "reference_id": "MONDO:0009332"
    }
  ],
  "children": [
    {
      "id": 14223,
      "label": "factor XIII, A subunit, deficiency of",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18203,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015633",
          "MEDGEN:442497",
          "MESH:C567691",
          "OMIM:613225",
          "SCTID:439455002",
          "UMLS:C2750514"
        ],
        "synonyms": [
          "factor XIII, A subunit, deficiency of",
          "factor XIIIA deficiency",
          "hereditary factor XIII A subunit deficiency",
          "hereditary factor XIII alpha subunit deficiency",
          "hereditary factor XIII type II deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0013187"
    },
    {
      "id": 14226,
      "label": "factor XIII, b subunit, deficiency of",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18203,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015635",
          "MEDGEN:442490",
          "MESH:C567688",
          "OMIM:613235",
          "UMLS:C2750481"
        ],
        "synonyms": [
          "factor XIII, b subunit, deficiency of",
          "factor XIIIB deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0013190"
    }
  ],
  "roots": [
    {
      "id": 4358,
      "label": "factor XIII deficiency"
    },
    {
      "id": 4360,
      "label": "hemorrhagic disease"
    },
    {
      "id": 10564,
      "label": "congenital hematological disorder"
    }
  ]
}