{
  "id": 18223,
  "label": "congenital fibrinogen deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018060",
  "properties": {
    "xrefs": [
      "GARD:0002320",
      "MEDGEN:9230",
      "Orphanet:335",
      "UMLS:C0019250",
      "icd11.foundation:1452989457"
    ],
    "synonyms": [
      "congenital fibrinogen deficiency",
      "fibrinogen deficiency, congenital"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Congenital deficiencies of fibrinogen are coagulation disorders characterized by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen. Afibrinogenemia (complete absence of fibrinogen) and hypofibrinogenemia (reduced plasma fibrinogen concentration) correspond to quantitative anomalies of fibrinogen while dysfibrinogenemia corresponds to a functional anomaly of fibrinogen. Hypo- and dysfibrinogenemia may be frequently combined (hypodysfibrinogenemia)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4359,
      "label": "coagulation protein disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2212",
          "GARD:0023096",
          "MEDGEN:108723",
          "MESH:D020147",
          "NCIT:C27215",
          "SCTID:86075001",
          "UMLS:C0600503"
        ],
        "synonyms": [
          "coagulation factor deficiency",
          "coagulation factor deficiency syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital or acquired deficiency of one of the coagulation factors. It results in bleeding."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002242"
    },
    {
      "id": 4360,
      "label": "hemorrhagic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2213",
          "ICD9:287.9",
          "MEDGEN:6799",
          "MESH:D006474",
          "NCIT:C115221",
          "UMLS:C0019087"
        ],
        "synonyms": [
          "bleeding diathesis",
          "bleeding disorder",
          "bleeding predisposition",
          "bleeding tendency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (blood coagulation disorders) or another abnormality causing a structural flaw in the blood vessels (hemostatic disorders)."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002243"
    }
  ],
  "children": [
    {
      "id": 15452,
      "label": "familial dysfibrinogenemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002004",
          "ICD9:286.3",
          "MEDGEN:82901",
          "NCIT:C131659",
          "OMIM:616004",
          "Orphanet:98881",
          "SCTID:111589005",
          "UMLS:C0272350"
        ],
        "synonyms": [
          "dysfibrinogenemia",
          "familial dysfibrinogenemia",
          "hypodysfibrinogenemia",
          "congenital dysfibrinogenemia",
          "dysfibrinogenemia, congenital",
          "dysfibrinogenemia, familial",
          "hypodysfibrinogenemia, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Familial dysfibrinogenemia is a coagulation disorder characterized by a bleeding tendency due to a functional anomaly of circulating fibrinogen."
      },
      "child_count": 1,
      "reference_id": "MONDO:0014452"
    }
  ],
  "roots": [
    {
      "id": 4359,
      "label": "coagulation protein disease"
    },
    {
      "id": 4360,
      "label": "hemorrhagic disease"
    }
  ]
}