{
  "id": 18229,
  "label": "trisomy X",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018066",
  "properties": {
    "xrefs": [
      "GARD:0005672",
      "MEDGEN:113140",
      "MESH:C535318",
      "NCIT:C129718",
      "NORD:1798",
      "Orphanet:3375",
      "SCTID:35111009",
      "UMLS:C0221033",
      "icd11.foundation:423644907"
    ],
    "synonyms": [
      "47,XXX",
      "47,XXX syndrome",
      "Triplo-X syndrome",
      "XXX syndrome",
      "triple X syndrome",
      "trisomy X",
      "trisomy type X",
      "47 XXX syndrome",
      "Triplo X syndrome",
      "triple-X chromosome syndrome",
      "triple-X female"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Trisomy X is a sex chromosome anomaly with a variable phenotype caused by the presence of an extra X chromosome in females (47,XXX instead of 46,XX)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 19578,
      "label": "inherited primary ovarian failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7067,
        16330,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019294",
          "MEDGEN:443920",
          "OMIMPS:311360",
          "Orphanet:95710",
          "UMLS:C2930861"
        ],
        "synonyms": [
          "hereditary primary ovarian failure",
          "inherited POI",
          "inherited premature ovarian failure",
          "inherited primary ovarian insufficiency",
          "non-acquired premature ovarian failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 164,
      "reference_id": "MONDO:0019852"
    },
    {
      "id": 24425,
      "label": "chromosome X disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19717
      ],
      "type_id": 0,
      "properties": {
        "definition": "Chromosomal disorder in which chromosome X is affected."
      },
      "child_count": 13,
      "reference_id": "MONDO:0700027"
    },
    {
      "id": 24461,
      "label": "trisomy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:21702",
          "MESH:D014314",
          "NCIT:C3421",
          "UMLS:C0041107"
        ],
        "synonyms": [
          "chromosomal triplication"
        ],
        "definition": "A chromosomal abnormality consisting of the presence of one chromosome in addition to the normal diploid number."
      },
      "child_count": 23,
      "reference_id": "MONDO:0700065"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 19578,
      "label": "inherited primary ovarian failure"
    },
    {
      "id": 24425,
      "label": "chromosome X disorder"
    },
    {
      "id": 24461,
      "label": "trisomy"
    }
  ]
}