{
  "id": 18249,
  "label": "double outlet right ventricle",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018089",
  "properties": {
    "xrefs": [
      "DOID:6406",
      "GARD:0001908",
      "ICD10CM:Q20.1",
      "MEDGEN:41649",
      "MESH:D004310",
      "MedDRA:10013611",
      "NANDO:1200710",
      "NANDO:2100076",
      "NANDO:2200256",
      "NCIT:C98916",
      "Orphanet:3426",
      "SCTID:204299009",
      "UMLS:C0013069",
      "icd11.foundation:141717788"
    ],
    "synonyms": [
      "DORV",
      "double outlet right ventricle"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Double outlet right ventricle (DORV) is a rare cono-truncal anomaly in which both the aorta and pulmonary artery originate, either entirely or predominantly, from the morphologic right ventricle."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4213,
      "label": "ventricular septal defect",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4221,
        24272
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1657",
          "HP:0001629",
          "ICD10CM:Q21.0",
          "ICD9:745.4",
          "MEDGEN:42366",
          "MESH:D006345",
          "NANDO:2100087",
          "NANDO:2200270",
          "NCIT:C84506",
          "OMIMPS:614429",
          "Orphanet:1480",
          "SCTID:30288003",
          "UMLS:C0018818",
          "icd11.foundation:668140715"
        ],
        "synonyms": [
          "VSD",
          "interventricular communication",
          "interventricular septal defect",
          "ventricular septal defect",
          "ventricular septal defect (disease)",
          "heart septal defects, ventricular",
          "ventricular septal defects"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "The presence of a defect (opening) in the septum that separates the two ventricles of the heart. It can be congenital or acquired."
      },
      "child_count": 10,
      "reference_id": "MONDO:0002070"
    },
    {
      "id": 17072,
      "label": "conotruncal heart malformations",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19327
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008189",
          "ICD9:747.11",
          "MEDGEN:341803",
          "NANDO:2200275",
          "OMIM:217095",
          "Orphanet:2445",
          "SCTID:218728005",
          "UMLS:C1857586"
        ],
        "synonyms": [
          "Taussig-Bing syndrome or defect",
          "conotruncal heart malformations",
          "conotruncal heart malformations, variable",
          "CTHM",
          "Double-outlet right ventricle",
          "conotruncal anomaly face syndrome",
          "conotruncal cardiac defects",
          "interrupted aortic Arch",
          "persistent truncus arteriosus",
          "truncus arteriosus communis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Conotruncal heart malformations are a group of congenital cardiac outflow tract anomalies that include such defects as tetralogy of Fallot, pulmonary atresia with ventricular septal defect, double-outlet right ventricle (DORV), double-outlet left ventricle, truncus arteriosus and transposition of the great arteries (TGA), among others. This group of defects is frequently found in patients with 22q11.2 deletion syndrome. A deletion of chromosome 22q11.2 has equally been associated in a subset of patients with various types of isolated non-syndromic conotruncal heart malformations (with the exception of DORV and TGA where this is very uncommon)."
      },
      "child_count": 8,
      "reference_id": "MONDO:0016581"
    }
  ],
  "children": [
    {
      "id": 18533,
      "label": "double outlet right ventricle with subaortic or doubly committed ventricular septal defect",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021755",
          "MEDGEN:1843284",
          "Orphanet:423693",
          "UMLS:C5680070"
        ],
        "synonyms": [
          "DORV with subaortic or doubly committed VSD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018498"
    },
    {
      "id": 18534,
      "label": "double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021756",
          "MEDGEN:1842277",
          "Orphanet:423712",
          "UMLS:C5680071"
        ],
        "synonyms": [
          "DORV with atrioventricular septal defect, pulmonary stenosis, heterotaxy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018499"
    },
    {
      "id": 19846,
      "label": "double outlet right ventricle with subaortic or doubly committed ventricular septal defect with pulmonary stenosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019615",
          "Orphanet:99043",
          "SCTID:253298003"
        ],
        "synonyms": [
          "DORV with subaortic or doubly committed VSD with pulmonary stenosis",
          "DORV, Fallot type",
          "double outlet right ventricle, Fallot type"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020386"
    },
    {
      "id": 19847,
      "label": "double outlet right ventricle with subpulmonary ventricular septal defect",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019616",
          "MEDGEN:365502",
          "Orphanet:99045",
          "SCTID:448794008",
          "UMLS:C1956412",
          "icd11.foundation:1963185163"
        ],
        "synonyms": [
          "DORV with subpulmonary VSD",
          "DORV-TGA",
          "Double outlet right ventricle with transposition of the great arteries",
          "Taussig-Bing syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020387"
    },
    {
      "id": 19848,
      "label": "double outlet right ventricle with non-committed subpulmonary ventricular septal defect",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18249
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019617",
          "MEDGEN:365501",
          "Orphanet:99046",
          "UMLS:C1956410",
          "icd11.foundation:2032277111"
        ],
        "synonyms": [
          "DORV with non-committed subpulmonary VSD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020388"
    }
  ],
  "roots": [
    {
      "id": 4213,
      "label": "ventricular septal defect"
    },
    {
      "id": 17072,
      "label": "conotruncal heart malformations"
    }
  ]
}