{
  "id": 18303,
  "label": "atypical hemolytic-uremic syndrome with DGKE deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018159",
  "properties": {
    "xrefs": [
      "GARD:0017543",
      "MEDGEN:1826167",
      "Orphanet:357008",
      "UMLS:C5679921"
    ],
    "synonyms": [
      "AHUS with DGKE deficiency",
      "D-HUS with DGKE deficiency",
      "atypical HUS with DGKE deficiency",
      "hemolytic-uremic syndrome without diarrhea with DGKE deficiency",
      "hemolytic-uremic syndrome without diarrhoea with DGKE deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16818,
      "label": "atypical hemolytic-uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5701,
        19495,
        25595
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080301",
          "GARD:0008702",
          "MEDGEN:444141",
          "MESH:D065766",
          "NANDO:1200473",
          "NANDO:1200474",
          "NANDO:2200131",
          "NANDO:2200641",
          "NCIT:C123223",
          "NORD:822",
          "Orphanet:2134",
          "UMLS:C2931788"
        ],
        "synonyms": [
          "Atypical Hemolytic Uremic Syndrome",
          "D-HUS",
          "aHUS",
          "atypical HUS",
          "atypical hemolytic uremic syndrome",
          "hemolytic-uremic syndrome without diarrhea",
          "hemolytic-uremic syndrome without diarrhoea",
          "non-diarrhea-associated hemolytic uremic syndrome",
          "D-minus hemolytic uremic syndrome (D-HUS)",
          "HUS, atypical"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction."
      },
      "child_count": 16,
      "reference_id": "MONDO:0016244"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16818,
      "label": "atypical hemolytic-uremic syndrome"
    }
  ]
}