{
  "id": 18416,
  "label": "atypical juvenile parkinsonism",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018321",
  "properties": {
    "xrefs": [
      "GARD:0017621",
      "MEDGEN:1380105",
      "Orphanet:391411",
      "SCTID:725146001",
      "UMLS:C4510873"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Atypical juvenile parkinsonism (AJP) is a complex form of young-onset Parkinson disease (YOPD) that manifests with pyramidal signs, eye movement abnormalities, psychiatric manifestations (depression, anxiety, drug-induced psychosis, and impulse control disorders), intellectual disability, and other neurological symptoms (such as ataxia and epilepsy) along with classical parkinsonian symptoms."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 20335,
      "label": "parkinsonian disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5849
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080855",
          "MEDGEN:66079",
          "MESH:D020734",
          "UMLS:C0242422"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA."
      },
      "child_count": 21,
      "reference_id": "MONDO:0021095"
    }
  ],
  "children": [
    {
      "id": 15237,
      "label": "juvenile onset Parkinson disease 19A",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3149,
        18416
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060891",
          "GARD:0018461",
          "MEDGEN:816141",
          "OMIM:615528",
          "UMLS:C3809811"
        ],
        "synonyms": [
          "DNAJC6 Parkinson disease",
          "Parkinson disease caused by mutation in DNAJC6",
          "juvenile onset Parkinson disease 19A",
          "juvenile onset Parkinson disease type 19A",
          "PARK19",
          "PARK19A",
          "Park19, formerly",
          "Parkinson disease 19, juvenile-onset",
          "Parkinson disease 19A, juvenile-onset",
          "Parkinson disease 19B, early-onset",
          "juvenile onset Parkinson's disease 19A"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any Parkinson disease in which the cause of the disease is a mutation in the DNAJC6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014231"
    }
  ],
  "roots": [
    {
      "id": 20335,
      "label": "parkinsonian disorder"
    }
  ]
}