{
  "id": 18432,
  "label": "periodic paralysis with later-onset distal motor neuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018343",
  "properties": {
    "xrefs": [
      "GARD:0021634",
      "MEDGEN:1670241",
      "Orphanet:397750",
      "UMLS:C4751573"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3261,
      "label": "familial periodic paralysis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6470,
        16738,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1029",
          "GARD:0021613",
          "MEDGEN:18291",
          "MESH:D010245",
          "NANDO:1200502",
          "NCIT:C84709",
          "Orphanet:371433",
          "SCTID:267607008",
          "UMLS:C0030443"
        ],
        "synonyms": [
          "familial periodic paralysis",
          "hereditary periodic paralysis (disease)",
          "familial periodic paralyses",
          "familial periodic paralyzes",
          "genetic periodic paralysis",
          "normokalemic periodic paralyses",
          "normokalemic periodic paralysis",
          "normokalemic periodic paralyzes",
          "paralysis, familial periodic",
          "paralysis, normokalemic periodic",
          "paralyzes, normokalemic periodic",
          "periodic paralysis, familial",
          "periodic paralysis, normokalemic",
          "periodic paralyzes, familial",
          "periodic paralyzes, normokalemic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of genetic neurological disorders caused by mutations in genes involved in the sodium and calcium channels in nerve cells. It is characterized by episodes of muscle paralysis in which the affected muscles become flaccid and the deep tendon reflexes disappear. Between the episodes the affected muscles usually work normally."
      },
      "child_count": 18,
      "reference_id": "MONDO:0000995"
    },
    {
      "id": 16918,
      "label": "mitochondrial oxidative phosphorylation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5908
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020546",
          "MEDGEN:1825947",
          "Orphanet:223713",
          "UMLS:C5679825",
          "icd11.foundation:1204111545"
        ],
        "synonyms": [
          "OXPHOS disease",
          "OXPHOS system deficiency"
        ],
        "definition": "A multisystem disorder with variable manifestations resulting from a defect in the mitochondrial oxidative phosphorylation (OXPHOS) system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0016387"
    },
    {
      "id": 24271,
      "label": "hereditary neuromuscular disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18957,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026275"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology that is characterized by progressive muscle degeneration and weakness."
      },
      "child_count": 44,
      "reference_id": "MONDO:0100546"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3261,
      "label": "familial periodic paralysis"
    },
    {
      "id": 16918,
      "label": "mitochondrial oxidative phosphorylation disorder"
    },
    {
      "id": 24271,
      "label": "hereditary neuromuscular disease"
    }
  ]
}