{
  "id": 18443,
  "label": "neonatal lupus erythematosus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018360",
  "properties": {
    "xrefs": [
      "EFO:0004537",
      "GARD:0021647",
      "MEDGEN:98372",
      "MESH:C536397",
      "NCIT:C99236",
      "NORD:1495",
      "Orphanet:398124",
      "SCTID:95609003",
      "UMLS:C0409979",
      "icd11.foundation:213855225"
    ],
    "synonyms": [
      "Neonatal Lupus",
      "congenital lupus",
      "congenital lupus erythematosus",
      "neonatal SLE",
      "neonatal lupus",
      "neonatal lupus syndrome",
      "neonatal systemic lupus erythematosus"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "A self-limited skin rash that appears in the neonatal period and usually resolves in four to six months after birth. It is caused by placental transfer of maternal autoantibodies, usually anti-Ro antibody. In a minority of cases, it is associated with congenital heart block, hepatitis, or thrombocytopenia. The mothers of the affected babies may be asymptomatic or suffer from systemic lupus erythematosus, Sjogren's syndrome, or rheumatoid arthritis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 9248,
      "label": "systemic lupus erythematosus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6454,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9074",
          "HP:0002725",
          "ICD10CM:M32",
          "ICD10WHO:M32",
          "ICD9:710.0",
          "MEDGEN:6146",
          "MESH:D008180",
          "NANDO:1200272",
          "NANDO:2200416",
          "NCIT:C3201",
          "NORD:1380",
          "OMIM:152700",
          "OMIMPS:601744",
          "Orphanet:536",
          "SCTID:55464009",
          "UMLS:C0024141",
          "icd11.foundation:749596428"
        ],
        "synonyms": [
          "Lupus",
          "SLE",
          "SLE - lupus erythematosus, systemic",
          "disseminated lupus erythematosus",
          "lupus erythematosus, systemic",
          "systemic lupus erythematosus",
          "systemic lupus erythematosus (disease)",
          "systemic lupus erythematosus susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific."
      },
      "child_count": 20,
      "reference_id": "MONDO:0007915"
    },
    {
      "id": 18439,
      "label": "secondary neonatal autoimmune disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021643",
          "MEDGEN:1842254",
          "Orphanet:398091",
          "UMLS:C5680041"
        ],
        "synonyms": [
          "Transplacentally acquired neonatal autoimmune disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0018356"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 9248,
      "label": "systemic lupus erythematosus"
    },
    {
      "id": 18439,
      "label": "secondary neonatal autoimmune disease"
    }
  ]
}