{
  "id": 18453,
  "label": "avascular necrosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018373",
  "properties": {
    "xrefs": [
      "GARD:0021658",
      "MEDGEN:10200",
      "NCIT:C34841",
      "Orphanet:399164",
      "SCTID:397758007",
      "UMLS:C0027543"
    ],
    "synonyms": [
      "AVN",
      "avascular necrosis of bone"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7060,
      "label": "osteonecrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080008",
          "DOID:10159",
          "EFO:0004259",
          "GARD:0021657",
          "ICD10CM:M87",
          "ICD10WHO:M87",
          "ICD9:732.3",
          "ICD9:733.4",
          "ICD9:733.41",
          "ICD9:733.42",
          "ICD9:733.43",
          "ICD9:733.44",
          "ICD9:733.49",
          "MEDGEN:45249",
          "MESH:D010020",
          "NCIT:C34880",
          "NCIT:C35476",
          "NORD:1537",
          "Orphanet:399158",
          "SCTID:240196003",
          "UMLS:C0029445",
          "icd11.foundation:536467755"
        ],
        "synonyms": [
          "bone necrosis",
          "ischaemic bone disease",
          "ischemic bone disease",
          "osteonecrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A none disease characterized by death of bone tissue due to a lack of blood supply."
      },
      "child_count": 7,
      "reference_id": "MONDO:0005380"
    }
  ],
  "children": [
    {
      "id": 3154,
      "label": "dysbaric osteonecrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18453
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080018",
          "GARD:0022834",
          "MEDGEN:782135",
          "SCTID:431591000124102",
          "UMLS:C3494941"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen embolism."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000840"
    },
    {
      "id": 18454,
      "label": "secondary avascular necrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18453
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021659",
          "MEDGEN:1842971",
          "Orphanet:399169",
          "UMLS:C5680036"
        ],
        "synonyms": [
          "secondary AVN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0018374"
    },
    {
      "id": 18458,
      "label": "primary avascular necrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18453
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021664",
          "MEDGEN:1842421",
          "Orphanet:399302",
          "UMLS:C5680038"
        ],
        "synonyms": [
          "primary AVN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 3,
      "reference_id": "MONDO:0018379"
    }
  ],
  "roots": [
    {
      "id": 7060,
      "label": "osteonecrosis"
    }
  ]
}