{
  "id": 18520,
  "label": "undifferentiated carcinoma of esophagus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018481",
  "properties": {
    "xrefs": [
      "GARD:0021742",
      "MEDGEN:412163",
      "NCIT:C27422",
      "Orphanet:418951",
      "UMLS:C2188058"
    ],
    "synonyms": [
      "esophageal undifferentiated carcinoma",
      "esophagus undifferentiated carcinoma",
      "oesophagus undifferentiated carcinoma",
      "undifferentiated esophageal cancer",
      "undifferentiated esophageal carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An esophageal carcinoma characterized by the absence of microscopic features of squamous differentiation. However, there is immunohistochemical evidence of squamous differentiation."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7225,
      "label": "esophageal squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3748",
          "EFO:0005922",
          "GARD:0018901",
          "MEDGEN:124635",
          "MESH:C562729",
          "MESH:D000077277",
          "NCIT:C4024",
          "ONCOTREE:ESCC",
          "Orphanet:99977",
          "SCTID:276804009",
          "UMLS:C0279626",
          "icd11.foundation:1417891145"
        ],
        "synonyms": [
          "ESCC",
          "esophageal epidermoid carcinoma",
          "esophageal scc",
          "esophageal squamous cell cancer",
          "esophageal squamous cell carcinoma",
          "esophagus scc",
          "esophagus squamous cell carcinoma",
          "oesophagus scc",
          "scc of esophagus",
          "scc of the esophagus",
          "scc of the oesophagus",
          "squamous cell car. - esophagus",
          "squamous cell car. - oesophagus",
          "squamous cell carcinoma of esophagus",
          "squamous cell carcinoma of oesophagus",
          "squamous cell carcinoma of the esophagus",
          "squamous cell carcinoma of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC) that can affect any part of the esophagus, but is usually located in the upper or middle third."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005580"
    },
    {
      "id": 7257,
      "label": "undifferentiated carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0006772",
          "ICDO:8020/3",
          "ICDO:8021/3",
          "MEDGEN:60010",
          "NCIT:C3692",
          "UMLS:C0205698"
        ],
        "synonyms": [
          "anaplastic carcinoma",
          "carcinoma, undifferentiated",
          "carcinoma, undifferentiated, malignant",
          "undifferentiated carcinoma"
        ],
        "definition": "A usually aggressive malignant epithelial neoplasm composed of atypical cells which do not display evidence of glandular, squamous, or transitional cell differentiation."
      },
      "child_count": 14,
      "reference_id": "MONDO:0005617"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7225,
      "label": "esophageal squamous cell carcinoma"
    },
    {
      "id": 7257,
      "label": "undifferentiated carcinoma"
    }
  ]
}