{
  "id": 18539,
  "label": "mesenchymal tumor of small intestine",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018506",
  "properties": {
    "xrefs": [
      "GARD:0021761",
      "MEDGEN:1843104",
      "Orphanet:423798",
      "UMLS:C5680077"
    ],
    "synonyms": [
      "mesenchymal tumor of small bowel",
      "mesenchymal tumour of small bowel"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6071,
      "label": "small intestine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20357,
        21546
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7505",
          "MEDGEN:91055",
          "NCIT:C4432",
          "SCTID:126832004",
          "UMLS:C0345832"
        ],
        "synonyms": [
          "neoplasm of small bowel",
          "neoplasm of small intestine",
          "neoplasm of the small bowel",
          "neoplasm of the small intestine",
          "small bowel neoplasm",
          "small bowel tumor",
          "small bowel tumour",
          "small intestinal neoplasm",
          "small intestine neoplasm",
          "small intestine neoplasm (disease)",
          "small intestine tumor",
          "small intestine tumour",
          "tumor of small bowel",
          "tumor of small intestine",
          "tumor of the small bowel",
          "tumor of the small intestine",
          "tumour of small bowel",
          "tumour of small intestine",
          "tumour of the small bowel",
          "tumour of the small intestine"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the small intestine. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0004251"
    }
  ],
  "children": [
    {
      "id": 5295,
      "label": "small intestine leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5296,
        6788,
        18539
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5271",
          "GARD:0019852",
          "MEDGEN:183086",
          "NCIT:C7085",
          "Orphanet:104076",
          "SCTID:716651004",
          "UMLS:C0920305",
          "icd11.foundation:389419378"
        ],
        "synonyms": [
          "leiomyosarcoma of small bowel",
          "leiomyosarcoma of small intestine",
          "leiomyosarcoma of the small bowel",
          "leiomyosarcoma of the small intestine",
          "small bowel leiomyosarcoma",
          "small intestinal leiomyosarcoma",
          "small intestine leiomyosarcoma",
          "smooth muscle connective tissue tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the small intestine. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003360"
    },
    {
      "id": 12806,
      "label": "gastrointestinal stromal tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        18539
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9253",
          "GARD:0008598",
          "ICD10CM:C49.A",
          "ICDO:8936/1",
          "MEDGEN:116049",
          "MESH:D046152",
          "MedDRA:10051066",
          "NCIT:C3868",
          "NORD:1174",
          "OMIM:606764",
          "ONCOTREE:GIST",
          "Orphanet:44890",
          "SCTID:420120006",
          "UMLS:C0238198"
        ],
        "synonyms": [
          "GIST",
          "Gastrointestinal Stromal Tumors",
          "gastrointestinal stromal neoplasm",
          "gastrointestinal stromal sarcoma",
          "gastrointestinal stromal tumor",
          "gastrointestinal stromal tumor (gist)",
          "gastrointestinal stromal tumor, familial, isolated cases",
          "gastrointestinal stromal tumor, isolated cases",
          "gastrointestinal stromal tumour (gist)",
          "gist",
          "gastrointestinal stromal tumors",
          "gastrointestinal stromal tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract, typically presenting in adults over the age of 40 (mean age 63), and only rarely in children, in various regions of the GI tract, most commonly the stomach or small intestine but also less commonly in the esophagus, appendix, rectum and colon. GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass, blood in stool, and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011719"
    }
  ],
  "roots": [
    {
      "id": 6071,
      "label": "small intestine neoplasm"
    }
  ]
}