{
  "id": 18543,
  "label": "epithelial tumor of the appendix",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018511",
  "properties": {
    "xrefs": [
      "GARD:0021766",
      "MEDGEN:1842930",
      "Orphanet:423982",
      "UMLS:C5680073"
    ],
    "synonyms": [
      "appendiceal epithelial tumor",
      "appendiceal epithelial tumour",
      "vermiform appendix epithelial neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A epithelial neoplasm that involves the vermiform appendix."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3476,
      "label": "appendiceal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7325,
        23661
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11240",
          "EFO:0003880",
          "GARD:0027340",
          "MEDGEN:1629",
          "MESH:D001063",
          "NCIT:C4434",
          "SCTID:126846004",
          "UMLS:C0003614"
        ],
        "synonyms": [
          "appendix neoplasm",
          "appendix tumor",
          "appendix tumour",
          "neoplasm of appendix",
          "neoplasm of the appendix",
          "neoplasm of vermiform appendix",
          "tumor of appendix",
          "tumor of the appendix",
          "tumor of vermiform appendix",
          "tumour of appendix",
          "tumour of the appendix",
          "tumour of vermiform appendix",
          "vermiform appendix neoplasm",
          "vermiform appendix neoplasm (disease)",
          "vermiform appendix tumor",
          "vermiform appendix tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm involving the appendix."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001236"
    },
    {
      "id": 21434,
      "label": "epithelial tumor of colon",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7078,
        7265
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "colon epithelial neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A epithelial neoplasm that involves the colon."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024479"
    }
  ],
  "children": [
    {
      "id": 5155,
      "label": "appendix carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3475,
        7615,
        18543
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4902",
          "GARD:0023407",
          "MEDGEN:196398",
          "NCIT:C9330",
          "SCTID:448992002",
          "UMLS:C0728951"
        ],
        "synonyms": [
          "appendix cancer",
          "appendix carcinoma",
          "carcinoma of appendix",
          "carcinoma of the appendix",
          "carcinoma of vermiform appendix",
          "vermiform appendix carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the vermiform appendix"
      },
      "child_count": 9,
      "reference_id": "MONDO:0003196"
    },
    {
      "id": 7663,
      "label": "appendix adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2975,
        18543
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000089",
          "GARD:0024287",
          "MEDGEN:312900",
          "NCIT:C43550",
          "UMLS:C1706829"
        ],
        "synonyms": [
          "appendix adenoma",
          "vermiform appendix adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A circumscribed neoplasm arising from the glandular epithelium of the appendix. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006088"
    },
    {
      "id": 16040,
      "label": "neuroendocrine tumor of the appendix, well differentiated, low or intermediate grade",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16041,
        18543,
        21454
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019754",
          "MEDGEN:474400",
          "NCIT:C96422",
          "ONCOTREE:AWDNET",
          "Orphanet:100079",
          "SCTID:725167001",
          "UMLS:C3272767",
          "icd11.foundation:1590340268"
        ],
        "synonyms": [
          "NEN of appendix",
          "appendiceal NEN",
          "appendiceal neuroendocrine neoplasm",
          "appendiceal neuroendocrine tumor",
          "appendiceal neuroendocrine tumour",
          "appendix NET",
          "appendix neuroendocrine tumor",
          "appendix neuroendocrine tumour",
          "appendix well differentiated endocrine tumor",
          "appendix well differentiated endocrine tumor/carcinoma",
          "appendix well differentiated endocrine tumour",
          "neuroendocrine neoplasm of appendix",
          "well-differentiated neuroendocrine tumor of the appendix",
          "well-differentiated neuroendocrine tumour of the appendix"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the appendix."
      },
      "child_count": 12,
      "reference_id": "MONDO:0015066"
    }
  ],
  "roots": [
    {
      "id": 3476,
      "label": "appendiceal neoplasm"
    },
    {
      "id": 21434,
      "label": "epithelial tumor of colon"
    }
  ]
}