{
  "id": 18596,
  "label": "primary polyarteritis nodosa",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018593",
  "properties": {
    "xrefs": [
      "GARD:0021830",
      "MEDGEN:1842954",
      "Orphanet:439737",
      "UMLS:C5680052"
    ],
    "synonyms": [
      "primary PAN",
      "primary periarteritis nodosa"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19045,
      "label": "polyarteritis nodosa",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23218
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9810",
          "GARD:0007360",
          "ICD10CM:M30.0",
          "ICD9:446.0",
          "MEDGEN:14681",
          "MESH:D010488",
          "MedDRA:10036024",
          "NANDO:1200261",
          "NANDO:2200425",
          "NCIT:C26847",
          "NORD:1588",
          "Orphanet:767",
          "SCTID:155441006",
          "UMLS:C0031036",
          "icd11.foundation:1419332129"
        ],
        "synonyms": [
          "Küssmaul-Maier disease",
          "PAN",
          "classic polyarteritis nodosa",
          "classical polyarteritis nodosa",
          "panarteritis nodosa",
          "periarteritis nodosa",
          "polyarteritis nodosa",
          "periarteritis",
          "polyarteritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Polyarteritis nodosa (PAN) is a rare, clinically heterogeneous, rheumatologic disease characterized by necrotizing inflammatory lesions affecting small- and medium-sized blood vessels. PAN most commonly affects skin, joints, peripheral nerves, the gut, and the kidney."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019170"
    }
  ],
  "children": [
    {
      "id": 18595,
      "label": "cutaneous polyarteritis nodosa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007415",
          "ICD9:709.8",
          "MEDGEN:83358",
          "NCIT:C117295",
          "Orphanet:439729",
          "SCTID:239926000",
          "UMLS:C0343190",
          "icd11.foundation:1752423171"
        ],
        "synonyms": [
          "cutaneous PAN",
          "cutaneous periarteritis nodosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Cutaneous polyarteritis nodosa (CPAN) is a rare limited form of polyarteritis nodosa (PAN), characterized by cutaneous vasculitis and mild and transient extracutaneous manifestations such as mild arthralgia, arthritis,myalgia, and rarely peripheral neuropathy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018592"
    },
    {
      "id": 18598,
      "label": "single-organ polyarteritis nodosa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021832",
          "MEDGEN:1842346",
          "Orphanet:439755",
          "UMLS:C5680051"
        ],
        "synonyms": [
          "single-organ PAN",
          "single-organ periarteritis nodosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Single-organ polyarteritis nodosa (PAN) is a rare, often mild form of PAN characterized by limited disease without generalized manifestations, most often affecting the skin (cutaneous PAN), the brain, eyes, pancreas, testicles, ureter, breasts, or ovaries. Affected patients are often younger than those with systemic PAN and relapses appear to be more common."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018595"
    },
    {
      "id": 18599,
      "label": "systemic polyarteritis nodosa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021833",
          "MEDGEN:1863875",
          "Orphanet:439762",
          "UMLS:C5848156"
        ],
        "synonyms": [
          "systemic PAN",
          "systemic periarteritis nodosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Systemic polyarteritis nodosa (PAN) is a chronic systemic necrotizingvasculitis of adults and childrenaffecting small- and medium-sized vessels and characterized by formation of microaneurysms leading to serious generalized disease and multi-organ involvement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018596"
    }
  ],
  "roots": [
    {
      "id": 19045,
      "label": "polyarteritis nodosa"
    }
  ]
}