{
  "id": 18635,
  "label": "pseudohypoaldosteronism",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018638",
  "properties": {
    "xrefs": [
      "DOID:4479",
      "GARD:0021861",
      "ICD9:255.8",
      "MEDGEN:18721",
      "MESH:D011546",
      "NANDO:2100133",
      "NANDO:2200367",
      "NCIT:C85034",
      "Orphanet:444916",
      "SCTID:77098009",
      "UMLS:C0033805"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "An inherited or acquired disorder of electrolyte metabolism, characterized by the inability of the renal tubules to respond to aldosterone. It is manifested by hyperkalemic metabolic acidosis, urinary salt wasting, normal or increased aldosterone secretion and normal glomerular filtration rate."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 8001,
      "label": "renal tubular transport disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:447",
          "EFO:1000647",
          "MEDGEN:19728",
          "MESH:D015499",
          "UMLS:C0035091"
        ],
        "synonyms": [
          "disorder of renal absorption",
          "renal absorption disease",
          "kidney tubular transport, inborn error",
          "kidney tubular transport, inborn errors",
          "renal tubular transport errors",
          "renal tubular transport, inborn error"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Genetic defects in the selective or non-selective transport functions of the kidney tubules."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006510"
    }
  ],
  "children": [
    {
      "id": 19433,
      "label": "transient pseudohypoaldosteronism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18635
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019176",
          "MEDGEN:900190",
          "Orphanet:93164",
          "SCTID:717263009",
          "UMLS:C4273962",
          "icd11.foundation:225064822"
        ],
        "synonyms": [
          "TPHA"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Transient pseudohypoaldosteronism is a renal tubulopathy characterized by renal tubular resistance to aldosterone, characterized by hyponatremia, metabolic acidosis and hyperkalemia and manifesting as dehydration, secondary to urinary tract malformation and infections in infants."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019643"
    },
    {
      "id": 24056,
      "label": "inherited pseudohypoaldosteronism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18635,
        23932
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026144"
        ],
        "synonyms": [
          "hereditary pseudohypoaldosteronism"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A form of pseudohypoaldosteronism that is characterized Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology."
      },
      "child_count": 4,
      "reference_id": "MONDO:0100323"
    }
  ],
  "roots": [
    {
      "id": 8001,
      "label": "renal tubular transport disease"
    }
  ]
}