{
  "id": 18652,
  "label": "hemophilia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018660",
  "properties": {
    "xrefs": [
      "DOID:0061030",
      "GARD:0010418",
      "MEDGEN:146334",
      "MedDRA:10061992",
      "NCIT:C3093",
      "Orphanet:448",
      "SCTID:90935002",
      "UMLS:C0684275"
    ],
    "synonyms": [
      "hemophilia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Hemophilia is a genetic disorder characterized by spontaneous hemorrhage or prolonged bleeding due to factor VIII or IX deficiency."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4359,
      "label": "coagulation protein disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2212",
          "GARD:0023096",
          "MEDGEN:108723",
          "MESH:D020147",
          "NCIT:C27215",
          "SCTID:86075001",
          "UMLS:C0600503"
        ],
        "synonyms": [
          "coagulation factor deficiency",
          "coagulation factor deficiency syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital or acquired deficiency of one of the coagulation factors. It results in bleeding."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002242"
    }
  ],
  "children": [
    {
      "id": 11751,
      "label": "hemophilia A",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2902,
        4360,
        18652,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12134",
          "GARD:0006591",
          "ICD10CM:D66",
          "ICD9:286.0",
          "MEDGEN:5501",
          "MESH:D006467",
          "MedDRA:10016080",
          "NANDO:2200676",
          "NCIT:C27146",
          "NORD:1221",
          "OMIM:134500",
          "OMIM:306700",
          "Orphanet:98878",
          "SCTID:234440005",
          "UMLS:C0019069",
          "icd11.foundation:337607970"
        ],
        "synonyms": [
          "congenital factor VIII disorder",
          "factor VIII deficiency",
          "haemophilia a, X-linked recessive",
          "haemophilia type A",
          "haemophilia type a",
          "hemophilia A",
          "hemophilia a, X-linked recessive",
          "hemophilia type A",
          "hemophilia type a",
          "hereditary Factor VIII deficiency",
          "hereditary Factor VIII deficiency disease",
          "HEMA",
          "Haemophilia A",
          "autosomal haemophilia a",
          "autosomal hemophilia a",
          "classic haemophilia",
          "classic hemophilia",
          "classical haemophilia",
          "classical hemophilia",
          "factor 8 deficiency",
          "haemophilia A, congenital",
          "hem A",
          "hemophilia A, congenital",
          "hemophilia, classic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "The most common form of hemophilia characterized by spontaneous or prolonged hemorrhages due to factor VIII deficiency."
      },
      "child_count": 20,
      "reference_id": "MONDO:0010602"
    },
    {
      "id": 11753,
      "label": "hemophilia B",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4360,
        18652,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12259",
          "GARD:0008732",
          "ICD10CM:D67",
          "ICD9:286.1",
          "MEDGEN:945",
          "MESH:D002836",
          "MedDRA:10016077",
          "NANDO:2200677",
          "NCIT:C26721",
          "NORD:1222",
          "OMIM:306900",
          "Orphanet:98879",
          "SCTID:41788008",
          "UMLS:C0008533",
          "icd11.foundation:1901375668"
        ],
        "synonyms": [
          "Christmas disease",
          "congenital factor IX deficiency",
          "congenital factor IX disorder",
          "factor IX deficiency",
          "haemophilia b, X-linked recessive",
          "haemophilia type B",
          "hemophilia B",
          "hemophilia b, X-linked recessive",
          "hemophilia type B",
          "hereditary Factor IX deficiency",
          "hereditary Factor IX deficiency disease",
          "F9 deficiency",
          "HEMB",
          "factor 9 deficiency",
          "haemophilia B Leyden",
          "haemophilia B(M)",
          "hem B",
          "hemophilia B Leyden",
          "hemophilia B(M)",
          "plasma thromboplastin component deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Hemophilia B is a form of hemophilia characterized by spontaneous or prolonged hemorrhages due to factor IX deficiency."
      },
      "child_count": 12,
      "reference_id": "MONDO:0010604"
    },
    {
      "id": 19017,
      "label": "acquired hemophilia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4360,
        18652,
        20034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010350",
          "ICD10CM:D68.311",
          "MEDGEN:204253",
          "MedDRA:10053745",
          "NANDO:1200898",
          "Orphanet:73274",
          "UMLS:C1096116"
        ],
        "synonyms": [
          "acquired hemophilia",
          "hemophilia, acquired"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Acquired hemophilia is a bleeding disorder that interferes with the body's blood clotting process. Signs and symptoms include prolonged bleeding, frequent nosebleeds, bruising throughout the body, solid swellings of congealed blood (hematomas), hematuria, and gastrointestinal or urologic bleeding. Acquired hemophilia occurs when the body's immune system attacks and disables a certain protein that helps the blood clot. About half of the cases are associated with other conditions, such as pregnancy, autoimmune disease, cancer, skin diseases, or allergic reactions to medications."
      },
      "child_count": 9,
      "reference_id": "MONDO:0019139"
    },
    {
      "id": 20024,
      "label": "factor XI deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18652
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025180",
          "MEDGEN:1386956",
          "MESH:D005173",
          "NANDO:2200679",
          "NCIT:C131739",
          "SCTID:767713001",
          "UMLS:C4321502"
        ],
        "synonyms": [
          "factor XI deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A coagulation disorder characterized by the partial or complete absence of factor XI activity in the blood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020587"
    }
  ],
  "roots": [
    {
      "id": 4359,
      "label": "coagulation protein disease"
    }
  ]
}