{
  "id": 18678,
  "label": "progressive muscular atrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018687",
  "properties": {
    "xrefs": [
      "DOID:318",
      "GARD:0021891",
      "ICD9:335.21",
      "MEDGEN:906831",
      "NCIT:C85027",
      "Orphanet:454706",
      "SCTID:88923002",
      "UMLS:C4082951",
      "icd11.foundation:1282359533"
    ],
    "synonyms": [
      "PMA",
      "pure progressive muscular atrophy"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare, milder form of amyotrophic lateral sclerosis. It is characterized by a slowly progressive clinical course. Signs and symptoms include muscle weakness, atrophy, and fasciculation."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6718,
      "label": "amyotrophic lateral sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5143,
        19749
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:332",
          "GARD:0005786",
          "HP:0007354",
          "ICD10CM:G12.21",
          "ICD9:335.20",
          "MEDGEN:274",
          "MESH:D000690",
          "MedDRA:10002026",
          "NANDO:1200002",
          "NCIT:C34373",
          "NORD:768",
          "Orphanet:803",
          "SCTID:86044005",
          "UMLS:C0002736",
          "birnlex:12566",
          "icd11.foundation:1982355687"
        ],
        "synonyms": [
          "ALS",
          "Charcot disease",
          "Lou Gehrig disease",
          "amyotrophic lateral sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004976"
    }
  ],
  "children": [
    {
      "id": 20759,
      "label": "adult progressive spinal muscular atrophy, Aran Duchenne type",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18678
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "Aran Duchenne spinal muscular atrophy",
          "adult SMA Aran Duchenne type",
          "adult progressive spinal muscular atrophy Aran Duchenne type"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A progressive muscle weakness and atrophy of the limbs that irregularly affects certain muscles, while it spares others."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021824"
    }
  ],
  "roots": [
    {
      "id": 6718,
      "label": "amyotrophic lateral sclerosis"
    }
  ]
}