{
  "id": 18741,
  "label": "KID syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018781",
  "properties": {
    "xrefs": [
      "GARD:0003113",
      "ICD9:759.89",
      "MEDGEN:777082",
      "MESH:C536168",
      "MedDRA:10048786",
      "NANDO:1200621",
      "NANDO:2200996",
      "NORD:1326",
      "OMIMPS:148210",
      "Orphanet:477",
      "SCTID:2625009",
      "UMLS:C3665333"
    ],
    "synonyms": [
      "KID/HID syndrome",
      "Keratitis Ichthyosis Deafness Syndrome",
      "Senter syndrome",
      "ichthyosis hystrix Rheydt type",
      "keratitis-ichthyosis-deafness/Hystrix-like ichthyosis-deafness syndrome",
      "keratitis, ichthyosis, and deafness (KID) syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Keratitis (and hystrix-like) ichthyosis deafness (KID/HID) syndrome is a rare congenital ectodermal disorder characterized by vascularizing keratitis, hyperkeratotic skin lesions and hearing loss."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 17917,
      "label": "diffuse palmoplantar keratoderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19132
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021289",
          "HP:0007435",
          "ICD9:757.39",
          "MEDGEN:7201",
          "Orphanet:307141",
          "SCTID:400123002",
          "UMLS:C0022584",
          "icd11.foundation:1259583500"
        ],
        "synonyms": [
          "diffuse PPK",
          "diffuse keratosis palmoplantaris",
          "diffuse palmoplantar hyperkeratosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Palmoplantar keratoderma that diffusely involves most of the palm and sole and is caused by a genetic abnormality."
      },
      "child_count": 32,
      "reference_id": "MONDO:0017666"
    },
    {
      "id": 19138,
      "label": "ectodermal dysplasia syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        20277,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2121",
          "GARD:0006317",
          "ICD9:757.31",
          "MEDGEN:8544",
          "MESH:D004476",
          "MedDRA:10010452",
          "NCIT:C84683",
          "OMIMPS:305100",
          "Orphanet:79373",
          "SCTID:8654005",
          "UMLS:C0013575",
          "icd11.foundation:1156567558"
        ],
        "synonyms": [
          "ectodermal dysplasia",
          "ectodermal dysplasia (select examples)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "The term ''ectodermal dysplasia'' defines a heterogeneous group of heritable disorders of the skin and its appendages characterized by the defective development of two or more ectodermal derivatives, including hair, teeth, nails, sweat glands and their modified structures (i.e. ceruminous, mammary and ciliary glands). The spectrum of clinical manifestations is wide and may include additional manifestations from other ectodermal, mesodermal and endodermal structures."
      },
      "child_count": 360,
      "reference_id": "MONDO:0019287"
    }
  ],
  "children": [
    {
      "id": 9186,
      "label": "autosomal dominant keratitis-ichthyosis-hearing loss syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2903,
        18741
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060871",
          "GARD:0024581",
          "MEDGEN:120536",
          "OMIM:148210",
          "UMLS:C0265336"
        ],
        "synonyms": [
          "KID syndrome, autosomal dominant",
          "keratitis-ichthyosis -deafness syndrome",
          "autosomal dominant keratitis-ichthyosis-deafness syndrome",
          "keratitis-ichthyosis-deafness syndrome, autosomal dominant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Autosomal dominant form of KID syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007850"
    },
    {
      "id": 10669,
      "label": "ichthyosiform erythroderma, corneal involvement, and hearing loss",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18741
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002946",
          "MEDGEN:224809",
          "MESH:C537363",
          "OMIM:242150",
          "SCTID:403780007",
          "UMLS:C1275089"
        ],
        "synonyms": [
          "ichthyosiform erythroderma, corneal involvement, and deafness",
          "Desmons syndrome",
          "KID syndrome, autosomal recessive",
          "ichthyosiform erythroderma, corneal involvement, deafness",
          "keratitis-ichthyosis-deafness syndrome, autosomal recessive"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0009440"
    },
    {
      "id": 12365,
      "label": "ichthyosis, hystrix-like, with hearing loss",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18741
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015349",
          "MEDGEN:355410",
          "MESH:C566528",
          "OMIM:602540",
          "UMLS:C1865234"
        ],
        "synonyms": [
          "hystrix-like ichthyosis with deafness",
          "ichthyosis, hystrix-like, with deafness",
          "HID syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011245"
    }
  ],
  "roots": [
    {
      "id": 17917,
      "label": "diffuse palmoplantar keratoderma"
    },
    {
      "id": 19138,
      "label": "ectodermal dysplasia syndrome"
    }
  ]
}