{
  "id": 18790,
  "label": "acquired purpura fulminans",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018854",
  "properties": {
    "xrefs": [
      "GARD:0018838",
      "MEDGEN:1377273",
      "MedDRA:10037556",
      "Orphanet:49566",
      "SCTID:725157006",
      "UMLS:C4510896"
    ],
    "synonyms": [
      "acquired PF",
      "acquired purpura fulminans"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. PF may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of PF that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic PF."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3138,
      "label": "purpura fulminans",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3483,
        4662
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060538",
          "GARD:0022830",
          "MEDGEN:88448",
          "MESH:D055665",
          "SCTID:13507004",
          "UMLS:C0085650",
          "icd11.foundation:1293848111"
        ],
        "synonyms": [
          "fibrinolytic purpura"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by disseminated intravascular coagulation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000809"
    },
    {
      "id": 3150,
      "label": "thrombotic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060903",
          "ICD9:453.9",
          "MEDGEN:21160",
          "MESH:D013927",
          "NCIT:C26891",
          "SCTID:439127006",
          "UMLS:C0040053"
        ],
        "synonyms": [
          "Clots, blood",
          "Thromboses",
          "blood Clots",
          "blood clot",
          "clot, blood",
          "thrombosis",
          "thrombotic disorder",
          "thrombus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "The formation of a blood clot in the lumen of a vessel or heart chamber; causes include coagulation disorders and vascular endothelial injury."
      },
      "child_count": 8,
      "reference_id": "MONDO:0000831"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3138,
      "label": "purpura fulminans"
    },
    {
      "id": 3150,
      "label": "thrombotic disease"
    }
  ]
}