{
  "id": 18792,
  "label": "lichen amyloidosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018856",
  "properties": {
    "xrefs": [
      "GARD:0018839",
      "MEDGEN:1830282",
      "Orphanet:49804",
      "SCTID:718105008",
      "UMLS:C5779561"
    ],
    "synonyms": [
      "amyloid lichen",
      "lichen amyloidosus"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Lichen amyloidosis is a rare chronic form of cutaneous amyloidosis, a skin disease characterized by the accumulation of amyloid deposits in the dermis, clinically characterized by the development of pruritic, often pigmented, hyperkeratotic papules on trunk and extremities, especially on the shins, and histologically by the deposition of amyloid or amyloid-like proteins in the papillary dermis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16181,
      "label": "primary cutaneous amyloidosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18960,
        20387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050639",
          "GARD:0000132",
          "MEDGEN:120635",
          "MESH:C562642",
          "MedDRA:10011659",
          "NCIT:C199391",
          "Orphanet:137807",
          "SCTID:282834007",
          "UMLS:C0268397"
        ],
        "synonyms": [
          "primary localised cutaneous amyloidosis",
          "primary localized cutaneous amyloidosis",
          "PLCA",
          "familial primary localised cutaneous amyloidosis",
          "familial primary localized cutaneous amyloidosis",
          "amyloidosis IX",
          "amyloidosis familial cutaneous lichen",
          "amyloidosis, primary localised cutaneous",
          "amyloidosis, primary localized cutaneous",
          "lichen amyloidosis familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Cutaneous amyloidosis refers to a variety of skin diseases characterized histologically by the extracellular accumulation of amyloid deposits in the dermis. Rare forms include lichen amyloidosus, X-linked reticulate pigmentary disorder, primary localized cutaneous nodular amyloidosis, and macular amyloidosis."
      },
      "child_count": 10,
      "reference_id": "MONDO:0015301"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16181,
      "label": "primary cutaneous amyloidosis"
    }
  ]
}