{
  "id": 18816,
  "label": "orbital leiomyoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018885",
  "properties": {
    "xrefs": [
      "GARD:0018845",
      "MEDGEN:930669",
      "Orphanet:52994",
      "SCTID:719045009",
      "UMLS:C4305000",
      "icd11.foundation:614302400"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Orbital leiomyoma is a rare benign smooth muscle tumor arising from the walls of orbital vessels characterized by its slow growth and well encapsulated nature. It is usually located in an extraconal position, commonly manifesting with painless proptosis. The tumor is composed of spindle cells arranged in a fibrous stroma rich in dilated sinusoidal capillaries. The nuclei of tumor cells are oval with blunted ends and there are no mitotic figures. Orbital leiomyoma when excised has excellent prognosis for vision and life. One case of orbital leiomyosarcoma that possibly represents sarcomatous change in an orbital leiomyoma following radiation treatment has been reported."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20431,
      "label": "eye neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7019,
        7231
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003824",
          "ICD10CM:C69-C72",
          "MEDGEN:5095",
          "NCIT:C3030",
          "ONCOTREE:EYE",
          "UMLS:C0015414"
        ],
        "synonyms": [
          "eye neoplasm (disease)",
          "eye tumor",
          "eye tumour",
          "eyeball of camera-type eye neoplasm",
          "eyeball of camera-type eye tumor",
          "eyeball of camera-type eye tumour",
          "neoplasm of eye",
          "neoplasm of eyeball of camera-type eye",
          "neoplasm of the eye",
          "ocular neoplasm",
          "ocular tumor",
          "ocular tumour",
          "tumor of eye",
          "tumor of eyeball of camera-type eye",
          "tumor of the eye",
          "tumour of eye",
          "tumour of eyeball of camera-type eye",
          "tumour of the eye"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A neoplasm (disease) that involves the eye."
      },
      "child_count": 26,
      "reference_id": "MONDO:0021220"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20431,
      "label": "eye neoplasm"
    }
  ]
}