{
  "id": 18841,
  "label": "hypotrichosis simplex",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0018914",
  "properties": {
    "xrefs": [
      "GARD:0009170",
      "MEDGEN:344257",
      "MESH:C537160",
      "Orphanet:55654",
      "SCTID:723362004",
      "UMLS:C1854310"
    ],
    "synonyms": [
      "hereditary hypotrichosis simplex"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Hypotrichosis simplex (HS) or hereditary hypotrichosis simplex (HHS) is characterized by reduced pilosity over the scalp and body (with sparse, thin, and short hair) in the absence of other anomalies."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 6660,
      "label": "alopecia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19134
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:987",
          "ICD9:704.0",
          "ICD9:704.00",
          "ICD9:704.09",
          "MEDGEN:7982",
          "MESH:D000505",
          "NCIT:C50575",
          "Orphanet:79364",
          "SCTID:56317004",
          "UMLS:C0002170",
          "icd11.foundation:1313926062"
        ],
        "synonyms": [
          "alopecia",
          "hair loss",
          "loss Of hair",
          "alopecia areata"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Hair loss usually from the scalp. It may result in bald spots or spread to the entire scalp or the entire epidermis. It may be androgenetic or caused by chemotherapeutic agents, compulsive hair pulling, autoimmune disorders or congenital conditions."
      },
      "child_count": 26,
      "reference_id": "MONDO:0004907"
    }
  ],
  "children": [
    {
      "id": 11384,
      "label": "hypotrichosis 8",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        9961,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110705",
          "GARD:0015247",
          "MEDGEN:481100",
          "MESH:C566950",
          "OMIM:278150",
          "UMLS:C3279470"
        ],
        "synonyms": [
          "HYPT8",
          "LAH3",
          "LPAR6 hypotrichosis",
          "hypotrichosis 8",
          "hypotrichosis caused by mutation in LPAR6",
          "hypotrichosis type 8",
          "hypotrichosis, localized, autosomal recessive 3",
          "woolly hair, autosomal recessive 1, with or without hypotrichosis",
          "wooly hair, autosomal recessive 1, with or without hypotrichosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the LPAR6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010206"
    },
    {
      "id": 12556,
      "label": "hypotrichosis 7",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        9961,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110704",
          "GARD:0008178",
          "MEDGEN:322969",
          "MESH:C536973",
          "OMIM:604379",
          "UMLS:C1836672"
        ],
        "synonyms": [
          "HYPT7",
          "LAH2",
          "LIPH hypotrichosis",
          "Lah2",
          "hypotrichosis 7",
          "hypotrichosis caused by mutation in LIPH",
          "hypotrichosis type 7",
          "hypotrichosis, localized, autosomal recessive 2",
          "total Mari type hypotrichosis,",
          "woolly hair, autosomal recessive 2 with or without hypotrichosis",
          "wooly hair, autosomal recessive 2 with or without hypotrichosis",
          "Mari type alopecia universalis congenita",
          "Wh/Ht",
          "alopecia universalis congenita, Mari type",
          "hypotrichosis, autosomal recessive",
          "hypotrichosis, total, Mari type",
          "total hypotrichosis, Mari type",
          "woolly hair, autosomal recessive 2, with or without hypotrichosis",
          "wooly hair, autosomal recessive 2, with or without hypotrichosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the LIPH gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011452"
    },
    {
      "id": 12646,
      "label": "hypotrichosis 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110698",
          "GARD:0024806",
          "MEDGEN:1644234",
          "OMIM:605389",
          "UMLS:C4551976"
        ],
        "synonyms": [
          "HHS",
          "APCDD1 hypotrichosis",
          "HTS",
          "HYPT1",
          "hereditary generalised hypotrichosis simplex",
          "hypotrichosis 1",
          "hypotrichosis caused by mutation in APCDD1",
          "hypotrichosis type 1",
          "hypotrichosis simplex, generalized, hereditary"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the APCDD1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011549"
    },
    {
      "id": 13006,
      "label": "hypotrichosis 6",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110703",
          "GARD:0015423",
          "MEDGEN:335812",
          "MESH:C564312",
          "OMIM:607903",
          "UMLS:C1842839"
        ],
        "synonyms": [
          "DSG4 hypotrichosis",
          "HYPT6",
          "LAH1",
          "Lah1",
          "autosomal recessive localised hypotrichosis",
          "hypotrichosis 6",
          "hypotrichosis caused by mutation in DSG4",
          "hypotrichosis type 6",
          "hypotrichosis, localized, autosomal recessive 1",
          "monilethrix-like hypotrichosis",
          "Htl",
          "hypotrichosis, localized, autosomal recessive"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the DSG4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011932"
    },
    {
      "id": 14673,
      "label": "hypotrichosis 9",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110706",
          "GARD:0015781",
          "MEDGEN:481882",
          "OMIM:614237",
          "UMLS:C3280252"
        ],
        "synonyms": [
          "HYPT9",
          "hypotrichosis 9",
          "hypotrichosis type 9",
          "hypt9"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A hypotrichosis that has material basis in an autosomal recessive mutation on chromosome 10q11.23-q22.3."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013649"
    },
    {
      "id": 14674,
      "label": "hypotrichosis 10",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110707",
          "GARD:0015782",
          "MEDGEN:481883",
          "OMIM:614238",
          "UMLS:C3280253"
        ],
        "synonyms": [
          "HYPT10",
          "hypotrichosis 10",
          "hypotrichosis type 10",
          "hypt10"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A hypotrichosis that has material basis in an autosomal recessive mutation on chromosome 7p22.3-p21.3."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013650"
    },
    {
      "id": 15037,
      "label": "hypotrichosis 11",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110708",
          "GARD:0015900",
          "MEDGEN:767323",
          "OMIM:615059",
          "UMLS:C3554409"
        ],
        "synonyms": [
          "HYPT11",
          "SNRPE hypotrichosis",
          "hypotrichosis 11",
          "hypotrichosis caused by mutation in SNRPE",
          "hypotrichosis type 11",
          "hypt11"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the SNRPE gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014027"
    },
    {
      "id": 15386,
      "label": "hypotrichosis 12",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5030,
        18841
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110709",
          "GARD:0016027",
          "MEDGEN:863000",
          "OMIM:615885",
          "UMLS:C4014563"
        ],
        "synonyms": [
          "HYPT12",
          "RPL21 hypotrichosis",
          "hypotrichosis 12",
          "hypotrichosis caused by mutation in RPL21",
          "hypotrichosis type 12",
          "hypt12"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hypotrichosis in which the cause of the disease is a mutation in the RPL21 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014384"
    }
  ],
  "roots": [
    {
      "id": 6660,
      "label": "alopecia"
    }
  ]
}