{
  "id": 18964,
  "label": "intrahepatic cholestasis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019072",
  "properties": {
    "xrefs": [
      "DOID:1852",
      "MEDGEN:3042",
      "MESH:D002780",
      "SCTID:235888006",
      "UMLS:C0008372"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A cholestasis characterized by impairment of the bile flow caused by obstruction located in the liver."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3937,
      "label": "cholestasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4900
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13580",
          "ICD9:576.2",
          "MEDGEN:925",
          "MESH:D002779",
          "SCTID:30144000",
          "UMLS:C0008370"
        ],
        "synonyms": [
          "obstruction of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Impairment of the bile flow caused by obstruction within the liver, or outside the liver in the bile duct system."
      },
      "child_count": 5,
      "reference_id": "MONDO:0001751"
    }
  ],
  "children": [
    {
      "id": 17613,
      "label": "familial intrahepatic cholestasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6878,
        18954,
        18964
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021119",
          "ICD9:576.8",
          "Orphanet:284385",
          "SCTID:74162007"
        ],
        "synonyms": [
          "hereditary intrahepatic cholestasis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of intrahepatic cholestasis that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 12,
      "reference_id": "MONDO:0017290"
    },
    {
      "id": 24156,
      "label": "intrahepatic cholestasis of pregnancy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18964
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070227",
          "GARD:0009804",
          "MEDGEN:82788",
          "MESH:C535932",
          "Orphanet:69665",
          "UMLS:C0268318",
          "icd11.foundation:1576251337"
        ],
        "synonyms": [
          "gravidic intrahepatic cholestasis",
          "intrahepatic cholestasis of pregnancy",
          "pregnancy related cholestasis",
          "pregnancy-related cholestasis",
          "recurrent intrahepatic cholestasis of pregnancy",
          "RICP",
          "cholestasis, intrahepatic of pregnancy",
          "familial intrahepatic cholestasis of pregnancy",
          "familial recurrent intrahepatic cholestasis of pregnancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile acid levels, and (iii) spontaneous relief of signs and symptoms within two to three weeks after delivery."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100429"
    }
  ],
  "roots": [
    {
      "id": 3937,
      "label": "cholestasis"
    }
  ]
}