{
  "id": 18985,
  "label": "autoimmune thrombocytopenia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019098",
  "properties": {
    "xrefs": [
      "GARD:0018906",
      "MEDGEN:116621",
      "MedDRA:10050245",
      "Orphanet:71203",
      "SCTID:128091003",
      "UMLS:C0242584"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An autoimmune form of thrombocytopenia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4196,
      "label": "thrombocytopenia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1588",
          "ICD9:287.5",
          "MEDGEN:52737",
          "MESH:D013921",
          "NCIT:C3408",
          "SCTID:302215000",
          "UMLS:C0040034",
          "icd11.foundation:683583694"
        ],
        "synonyms": [
          "platelet count decreased",
          "thrombocytopenic disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002049"
    },
    {
      "id": 8586,
      "label": "autoimmune disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:417",
          "EFO:0005809",
          "ICD9:279.4",
          "ICD9:279.49",
          "ICD9:720",
          "MEDGEN:2135",
          "MESH:D001327",
          "NCIT:C2889",
          "OBI:1110054",
          "OMIM:109100",
          "SCTID:85828009",
          "UMLS:C0004364"
        ],
        "synonyms": [
          "autoimmune disease",
          "autoimmune disease or disorder",
          "autoimmune disorder",
          "disease, autoimmune",
          "autoimmune hypersensitivity disease",
          "hypersensitivity reaction type II disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to their own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis)."
      },
      "child_count": 47,
      "reference_id": "MONDO:0007179"
    }
  ],
  "children": [
    {
      "id": 9845,
      "label": "autoimmune thrombocytopenic purpura",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6463,
        18985,
        23244
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8924",
          "EFO:0007160",
          "GARD:0005194",
          "ICD10CM:D69.3",
          "ICD9:287.31",
          "MEDGEN:584986",
          "MedDRA:10021245",
          "NANDO:1200315",
          "NANDO:2200645",
          "NCIT:C3446",
          "OMIM:188030",
          "Orphanet:3002",
          "UMLS:C0398650",
          "icd11.foundation:364346400"
        ],
        "synonyms": [
          "immune thrombocytopenia",
          "ITP",
          "autoimmune thrombocytopenic purpura",
          "idiopathic thrombocytopenia",
          "idiopathic thrombocytopenia purpura",
          "idiopathic thrombocytopenic purpura",
          "thrombocytopenic purpura, autoimmune",
          "AITP",
          "immune thrombocytopenic purpura",
          "thrombocytopenic purpura autoimmune"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008558"
    },
    {
      "id": 16668,
      "label": "Evans syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6463,
        18985,
        19736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8931",
          "GARD:0006389",
          "ICD10CM:D69.41",
          "ICD9:287.32",
          "MEDGEN:75773",
          "MESH:C536380",
          "MedDRA:10053873",
          "NANDO:1200310",
          "NCIT:C61284",
          "NORD:1112",
          "Orphanet:1959",
          "SCTID:75331009",
          "UMLS:C0272126",
          "icd11.foundation:1048228553"
        ],
        "synonyms": [
          "Evans' syndrome",
          "autoimmune hemolytic anaemia and autoimmune thrombocytopenia",
          "autoimmune hemolytic anemia and autoimmune thrombocytopenia",
          "immune pancytopenia",
          "Evan syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Evans syndrome is a rare chronic hematologic disorder characterized by the simultaneous or sequential association of autoimmune hemolytic anemia (AIHA; a disorder in which auto-antibodies are directed against red blood cells causing anemia of varying degrees of severity) with immune thrombocytopenic purpura (ITP; a coagulation disorder in which auto-antibodies are directed against platelets causing hemorrhagic episodes) and occasionally autoimmune neutropenia, in the absence of a known underlying etiology."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016030"
    }
  ],
  "roots": [
    {
      "id": 4196,
      "label": "thrombocytopenia"
    },
    {
      "id": 8586,
      "label": "autoimmune disease"
    }
  ]
}