{
  "id": 18986,
  "label": "neuromyelitis optica",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019100",
  "properties": {
    "xrefs": [
      "DOID:8869",
      "EFO:0004256",
      "GARD:0006267",
      "ICD10CM:G36.0",
      "ICD9:341.0",
      "MEDGEN:45063",
      "MESH:D009471",
      "MedDRA:10029322",
      "NANDO:1200027",
      "NANDO:2201322",
      "NCIT:C84934",
      "NORD:1505",
      "Orphanet:71211",
      "SCTID:25044007",
      "UMLS:C0027873",
      "icd11.foundation:744293382"
    ],
    "synonyms": [
      "Devic disease",
      "Neuromyelitis Optica Spectrum Disorder",
      "Devic syndrome",
      "Devic's neuromyelitis optica",
      "NMO"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A rare inflammatory disease of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis (ON) and acute myelitis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6799,
      "label": "nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:863",
          "EFO:0000618",
          "ICD10CM:G00-G99",
          "ICD9:349.89",
          "ICD9:349.9",
          "MEDGEN:14336",
          "MESH:D009422",
          "NCIT:C26835",
          "SCTID:118940003",
          "UMLS:C0027765",
          "Wikipedia:Nervous_system_disease"
        ],
        "synonyms": [
          "disease of nervous system",
          "disease or disorder of nervous system",
          "disorder of nervous system",
          "nervous system disease",
          "nervous system disease or disorder",
          "nervous system disorder",
          "neurologic disease",
          "neurologic disorder",
          "neurological disease",
          "neurological disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005071"
    },
    {
      "id": 23388,
      "label": "autoimmune/inflammatory optic neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022037",
          "MEDGEN:1842963",
          "Orphanet:499047",
          "UMLS:C5681239"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0044685"
    }
  ],
  "children": [
    {
      "id": 22882,
      "label": "neuromyelitis optica spectrum disorder with anti-AQP4 antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18986
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022372",
          "MEDGEN:1842475",
          "Orphanet:592850",
          "UMLS:C5680295",
          "icd11.foundation:73324466"
        ],
        "synonyms": [
          "NMOSD with anti-AQP4 antibodies",
          "Neuromyelitis optica spectrum disorder with anti-aquaporin 4 antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035663"
    },
    {
      "id": 22883,
      "label": "neuromyelitis optica spectrum disorder with anti-MOG antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18986,
        29255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022373",
          "MEDGEN:1843203",
          "Orphanet:592856",
          "UMLS:C5680296",
          "icd11.foundation:605048789"
        ],
        "synonyms": [
          "NMOSD with anti-MOG antibodies",
          "Neuromyelitis optica spectrum disorder with anti-myelin oligodendrocyte glycoprotein antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035664"
    },
    {
      "id": 22884,
      "label": "neuromyelitis optica spectrum disorder without anti-MOG and without anti-AQP4 antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18986
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022374",
          "MEDGEN:1842615",
          "Orphanet:592869",
          "UMLS:C5680297"
        ],
        "synonyms": [
          "NMOSD without anti-MOG antibodies and without anti-AQP4 antibodies",
          "Neuromyelitis optica spectrum disorder without anti-Myelin oligodendrocyte glycoprotein and without anti-Aquaporin-4 antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035665"
    }
  ],
  "roots": [
    {
      "id": 6799,
      "label": "nervous system disorder"
    },
    {
      "id": 23388,
      "label": "autoimmune/inflammatory optic neuropathy"
    }
  ]
}