{
  "id": 19003,
  "label": "pneumocystosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019121",
  "properties": {
    "xrefs": [
      "DOID:11339",
      "EFO:0007448",
      "GARD:0004386",
      "ICD10CM:B59",
      "ICD9:136.3",
      "MEDGEN:777048",
      "MESH:D011020",
      "NCIT:C3334",
      "NORD:1923",
      "Orphanet:723",
      "SCTID:415125002",
      "UMLS:C1535939",
      "icd11.foundation:404370038"
    ],
    "synonyms": [
      "PCP",
      "PJP",
      "Pneumocystis",
      "Pneumocystis Pneumonia",
      "Pneumocystis carinii pneumonia",
      "Pneumocystis jirovecii pneumonia",
      "Pneumocystis pneumonia",
      "pneumocystosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localized to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4420,
      "label": "opportunistic mycosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2473",
          "ICD9:117.9",
          "ICD9:118",
          "MEDGEN:508004",
          "SCTID:78999002",
          "UMLS:C0029119"
        ],
        "synonyms": [
          "opportunistic systemic mycoses"
        ],
        "definition": "A mycosis that arises from infection in an immunologically compromised host."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002312"
    },
    {
      "id": 6953,
      "label": "pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21378,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:552",
          "EFO:0003106",
          "ICD10CM:J15",
          "ICD10CM:J18.9",
          "ICD9:483",
          "ICD9:483.8",
          "ICD9:484.8",
          "ICD9:486",
          "MEDGEN:10813",
          "MESH:D011014",
          "NCIT:C3333",
          "SCTID:233604007",
          "UMLS:C0032285",
          "icd11.foundation:142052508"
        ],
        "synonyms": [
          "acute pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005249"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007278",
          "MEDGEN:6144",
          "MESH:D008172",
          "UMLS:C0024116"
        ],
        "synonyms": [
          "Fungi caused lung disease",
          "Fungi lung disease",
          "fungal disease, pulmonary",
          "fungal diseases, pulmonary",
          "fungal infection, pulmonary",
          "fungal infections, pulmonary",
          "fungal lung disease",
          "fungal lung diseases",
          "lung disease, fungal",
          "pulmonary fungal disease",
          "pulmonary fungal diseases",
          "pulmonary fungal infection",
          "pulmonary fungal infections"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pulmonary diseases caused by fungal infections, usually through hematogenous spread."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005766"
    },
    {
      "id": 7525,
      "label": "Pneumocystis infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007447",
          "MEDGEN:163415",
          "MESH:D016720",
          "UMLS:C0851886"
        ],
        "synonyms": [
          "Pneumocystis infection",
          "infections, Pneumocystis"
        ],
        "definition": "Infections with species in the genus pneumocystis, a fungus causing interstitial plasma cell pneumonia (pneumonia, pneumocystis) and other infections in humans and other mammals. Immunocompromised patients, especially those with aids, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005923"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4420,
      "label": "opportunistic mycosis"
    },
    {
      "id": 6953,
      "label": "pneumonia"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease"
    },
    {
      "id": 7525,
      "label": "Pneumocystis infectious disease"
    }
  ]
}