{
  "id": 19023,
  "label": "hereditary thrombophilia due to congenital protein C deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019145",
  "properties": {
    "xrefs": [
      "DOID:3756",
      "GARD:0016544",
      "MEDGEN:671121",
      "MESH:C535424",
      "MESH:D020151",
      "NANDO:1201080",
      "NANDO:2100197",
      "NANDO:2200689",
      "NCIT:C99025",
      "NORD:1899",
      "Orphanet:745",
      "SCTID:76407009",
      "UMLS:C0598221",
      "icd11.foundation:2021932081"
    ],
    "synonyms": [
      "Protein C Deficiency",
      "Protein C deficiency",
      "Protein C deficiency disease",
      "hereditary thrombophilia due to congenital protein C deficiency",
      "protein C deficiency",
      "severe hereditary thrombophilia due to congenital protein C deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Congenital protein C deficiency is an inherited coagulation disorder characterized by deep venous thrombosis symptoms due to reduced synthesis and/or activity levels of protein C."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 23980,
      "label": "inherited thrombophilia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4413,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026094",
          "MEDGEN:391721",
          "OMIMPS:188050",
          "UMLS:C2584620"
        ],
        "synonyms": [
          "hereditary hypercoagulable disorder",
          "hereditary thrombophilia",
          "thrombophilia, hereditary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of thrombophilia that is inherited."
      },
      "child_count": 24,
      "reference_id": "MONDO:0100240"
    }
  ],
  "children": [
    {
      "id": 9622,
      "label": "thrombophilia due to protein C deficiency, autosomal dominant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19023
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0111909",
          "GARD:0018574",
          "MEDGEN:436138",
          "OMIM:176860",
          "UMLS:C2674321"
        ],
        "synonyms": [
          "thrombophilia 3 due to protein C deficiency, autosomal dominant",
          "thrombophilia due to protein C deficiency, autosomal dominant",
          "Proc deficiency, autosomal dominant",
          "Protein C deficiency, acquired",
          "Protein C deficiency, autosomal dominant",
          "THPH3",
          "thrombophilia due to PROTEIN C deficiency, autosomal dominant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008316"
    },
    {
      "id": 13900,
      "label": "thrombophilia due to protein C deficiency, autosomal recessive",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19023
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0111904",
          "GARD:0013041",
          "MEDGEN:394120",
          "MESH:C567353",
          "OMIM:612304",
          "UMLS:C2676759"
        ],
        "synonyms": [
          "thrombophilia 3 due to protein C deficiency, autosomal recessive",
          "thrombophilia due to protein C deficiency, autosomal recessive",
          "Proc deficiency, autosomal recessive",
          "Protein C deficiency, autosomal recessive",
          "THPH4",
          "autosomal recessive hereditary thrombophilia due to protein C deficiency",
          "autosomal recessive protein C deficiency",
          "hereditary thrombophilia due to PC deficiency",
          "hereditary thrombophilia due to congenital protein C deficiency",
          "thrombophilia due to PROTEIN C deficiency, autosomal recessive"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012860"
    }
  ],
  "roots": [
    {
      "id": 23980,
      "label": "inherited thrombophilia"
    }
  ]
}