{
  "id": 19127,
  "label": "SAPHO syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019266",
  "properties": {
    "xrefs": [
      "DOID:13677",
      "EFO:1001164",
      "GARD:0007606",
      "ICD9:706.1",
      "MEDGEN:120490",
      "MESH:D020083",
      "MedDRA:10051316",
      "NCIT:C119049",
      "Orphanet:793",
      "SCTID:60684003",
      "UMLS:C0263859",
      "icd11.foundation:1901494067"
    ],
    "synonyms": [
      "PPHS",
      "Pustulo-psoriatic hyperostotic Spondyloarthritis",
      "synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome",
      "synovitis-acne-pustulosis-hyperostosis-osteitis syndrome",
      "acquired hyperostosis syndrome",
      "synovitis acne pustulosis hyperostosis osteitis",
      "synovitis, acne, Pustlosis, hyperostosis, and osteomyelitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "SAPHO syndrome (acronym for Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is an auto-inflammatory disease, mainly characterized by the association of neutrophilic cutaneous involvement and chronic osteomyelitis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19503,
      "label": "autoinflammatory syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        7203
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051000",
          "ICD10CM:M04-M04",
          "MEDGEN:855741",
          "MedDRA:10072220",
          "NANDO:2100156",
          "NCIT:C119050",
          "Orphanet:93665",
          "UMLS:C3890737"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease."
      },
      "child_count": 74,
      "reference_id": "MONDO:0019751"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19503,
      "label": "autoinflammatory syndrome"
    }
  ]
}