{
  "id": 19139,
  "label": "skin pigmentation disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019288",
  "properties": {
    "xrefs": [
      "DOID:10123",
      "ICD9:709.09",
      "MEDGEN:316465",
      "MESH:D010859",
      "NCIT:C34557",
      "Orphanet:79374",
      "UMLS:C1704421"
    ],
    "synonyms": [
      "pigmentation anomaly of the skin",
      "pigmentation disease of zone of skin",
      "zone of skin pigmentation disease",
      "pigmentation disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A pigmentation disease that involves the zone of skin."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6820,
      "label": "skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:37",
          "EFO:0000701",
          "ICD9:702",
          "ICD9:702.8",
          "ICD9:709.8",
          "MEDGEN:20777",
          "MESH:D012871",
          "NANDO:2100281",
          "NCIT:C3371",
          "SCTID:95320005",
          "UMLS:C0037274"
        ],
        "synonyms": [
          "cutaneous disorder",
          "disease of zone of skin",
          "disease or disorder of zone of skin",
          "disorder of skin",
          "disorder of zone of skin",
          "skin diseases and manifestations",
          "skin disorder",
          "zone of skin disease",
          "zone of skin disease or disorder",
          "dermatosis",
          "genodermatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005093"
    }
  ],
  "children": [
    {
      "id": 2731,
      "label": "reticulate pigment disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19139,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022712",
          "OMIMPS:179850"
        ],
        "synonyms": [
          "reticulate pigment disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0000118"
    },
    {
      "id": 17067,
      "label": "hypo- and hypermelanotic cutaneous macules-retarded growth-intellectual disability syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0003347",
          "MEDGEN:371988",
          "MESH:C537836",
          "OMIM:154000",
          "Orphanet:2435",
          "SCTID:733469003",
          "UMLS:C1835172"
        ],
        "synonyms": [
          "Westerhof-Beemer-Cormane syndrome",
          "Westerhof Beemer Cormane syndrome",
          "congenital hypomelanotic and hypermelanotic macules",
          "hereditary congenital hypopigmented and hyperpigmented macules",
          "macules hereditary congenital hypopigmented and hyperpigmented",
          "macules, hereditary congenital hypopigmented and hyperpigmented"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Hypo- and hypermelanotic cutaneous macules-retarded growth-intellectual disability syndrome is a neurocutaneous syndrome characterized by congenital hypomelanotic and hypermelanotic cutaneous macules. It has been described in individuals spanning three generations of an Indian family. Some of the patients also had retarded growth and intellectual deficit."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016574"
    },
    {
      "id": 19140,
      "label": "hyperpigmentation of the skin",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "HP:0000953",
          "ICD9:709.09",
          "MEDGEN:57992",
          "Orphanet:79375",
          "SCTID:49765009",
          "UMLS:C0162834"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 24,
      "reference_id": "MONDO:0019289"
    },
    {
      "id": 19141,
      "label": "hypopigmentation of the skin",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "HP:0001010",
          "MEDGEN:102477",
          "MESH:D017496",
          "MedDRA:10040868",
          "Orphanet:79376",
          "UMLS:C0162835"
        ],
        "synonyms": [
          "hypopigmentation of the skin",
          "hypopigmentation of the skin (disease)",
          "hypomelanoses",
          "hypomelanosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections."
      },
      "child_count": 10,
      "reference_id": "MONDO:0019290"
    }
  ],
  "roots": [
    {
      "id": 6820,
      "label": "skin disorder"
    }
  ]
}