{
  "id": 19158,
  "label": "follicular atrophoderma-basal cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019317",
  "properties": {
    "xrefs": [
      "GARD:0025135",
      "Orphanet:79459"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7027,
      "label": "skin basal cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        20201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-2719",
          "DOID:2513",
          "HP:0002671",
          "ICDO:8090/3",
          "MEDGEN:1648304",
          "NCIT:C2921",
          "ONCOTREE:BCC",
          "SCTID:254701007",
          "UMLS:C4721806"
        ],
        "synonyms": [
          "BCC",
          "basal cell cancer",
          "basal cell carcinoma",
          "basal cell tumor",
          "basal cell tumour",
          "basal cell tumour (morphologic abnormality)",
          "malignant basal cell tumour",
          "malignant basal cell tumour (morphologic abnormality)",
          "basal cell carcinoma of skin",
          "basal cell carcinoma of the skin",
          "basal cell epithelioma",
          "basal cell skin carcinoma",
          "skin basal cell cancer",
          "skin basal cell carcinoma",
          "epithelioma basal cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas."
      },
      "child_count": 50,
      "reference_id": "MONDO:0005341"
    },
    {
      "id": 11690,
      "label": "Bazex-Dupre-Christol syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000838",
          "ICD9:757.39",
          "MEDGEN:87539",
          "OMIM:301845",
          "Orphanet:113",
          "Orphanet:166113",
          "SCTID:238640007",
          "SCTID:254820002",
          "UMLS:C0346104"
        ],
        "synonyms": [
          "BDCS",
          "Bazex syndrome",
          "Bazex syndrome, X-linked dominant",
          "Bazex-Dupre-Christol syndrome",
          "Bazex-Dupré-Christol syndrome",
          "acrokeratosis of Bazex",
          "acrokeratosis paraneoplastica",
          "acrokeratosis paraneoplastica of Bazex",
          "follicular atrophoderma and basal cell carcinomas",
          "BZX",
          "follicular atrophoderma-basal cell carcinoma syndrome",
          "follicular atrophoderma-basocellular proliferations-hypotrichosis syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Bazex-Dupre-Christol syndrome is a rare genodermatosis (hereditary skin disease) with a predisposition to early-onset basal cell carcinomas."
      },
      "child_count": 1,
      "reference_id": "MONDO:0010535"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7027,
      "label": "skin basal cell carcinoma"
    },
    {
      "id": 11690,
      "label": "Bazex-Dupre-Christol syndrome"
    }
  ]
}