{
  "id": 19178,
  "label": "sarcoidosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019338",
  "properties": {
    "xrefs": [
      "DOID:11335",
      "GARD:0007607",
      "ICD10CM:D86",
      "ICD10WHO:D86",
      "MEDGEN:48554",
      "MESH:D012507",
      "MedDRA:10039486",
      "NANDO:1200415",
      "NCIT:C34995",
      "NORD:1690",
      "Orphanet:797",
      "SCTID:31541009",
      "UMLS:C0036202",
      "icd11.foundation:330792642"
    ],
    "synonyms": [
      "Besnier-Boeck-Schaumann disease",
      "Boeck sarcoid",
      "Boeck's sarcoid",
      "Boeck's sarcoidosis",
      "Darier-Roussy sarcoid",
      "besnier-Boeck-Schaumann syndrome",
      "sarcoid",
      "sarcoidosis",
      "benign lymphogranulomatosis of Schaumann",
      "lupus pernio of Besnier",
      "miliary lupoid of boeck"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 19503,
      "label": "autoinflammatory syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        7203
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051000",
          "ICD10CM:M04-M04",
          "MEDGEN:855741",
          "MedDRA:10072220",
          "NANDO:2100156",
          "NCIT:C119050",
          "Orphanet:93665",
          "UMLS:C3890737"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease."
      },
      "child_count": 74,
      "reference_id": "MONDO:0019751"
    }
  ],
  "children": [
    {
      "id": 3895,
      "label": "cardiac sarcoidosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16883,
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13405",
          "GARD:0022992",
          "MEDGEN:140260",
          "NCIT:C35589",
          "SCTID:75403004",
          "UMLS:C0392077"
        ],
        "synonyms": [
          "heart sarcoidosis",
          "sarcoidosis of heart"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Sarcoidosis affecting the tissues of the heart."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001707"
    },
    {
      "id": 3896,
      "label": "pulmonary sarcoidosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17421,
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13406",
          "GARD:0022993",
          "ICD10CM:D86.0",
          "ICD9:517.8",
          "MEDGEN:19873",
          "MESH:D017565",
          "NCIT:C34997",
          "SCTID:24369008",
          "UMLS:C0036205"
        ],
        "synonyms": [
          "lung sarcoidosis",
          "sarcoidosis of lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001708"
    },
    {
      "id": 3897,
      "label": "hypercalcemic sarcoidosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13407",
          "GARD:0022994",
          "MEDGEN:272729",
          "NCIT:C35807",
          "UMLS:C1334067"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Sarcoidosis with a complication of hypercalcemia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001709"
    },
    {
      "id": 8086,
      "label": "skin sarcoidosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6820,
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13402",
          "EFO:1000767",
          "GARD:0024444",
          "ICD10CM:D86.3",
          "MEDGEN:19872",
          "NCIT:C34996",
          "SCTID:55941000",
          "UMLS:C0036203",
          "Wikipedia:Cutaneous_manifestations_of_sarcoidosis"
        ],
        "synonyms": [
          "cutaneous sarcoidosis",
          "sarcoidosis of zone of skin",
          "zone of skin sarcoidosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Formation of non-necrotizing granulomas in the skin. It may be a manifestation of systemic sarcoidosis or may also arise in isolation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006611"
    },
    {
      "id": 8432,
      "label": "uveoparotid fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13404",
          "EFO:1001232",
          "GARD:0024517",
          "MEDGEN:22600",
          "MESH:D014608",
          "SCTID:4416007",
          "UMLS:C0042171",
          "icd11.foundation:2079034902"
        ],
        "synonyms": [
          "uveoparotid fever"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A manifestation of sarcoidosis marked by chronic inflammation of the parotid gland and the uvea."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007011"
    },
    {
      "id": 9814,
      "label": "Blau syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19178,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050678",
          "GARD:0000304",
          "ICD9:692.9",
          "ICD9:714.89",
          "MEDGEN:1684759",
          "MESH:C538157",
          "MedDRA:10071755",
          "NANDO:1200476",
          "NANDO:2200434",
          "NCIT:C116794",
          "OMIM:186580",
          "OMIM:609464",
          "Orphanet:90340",
          "Orphanet:90341",
          "SCTID:699861000",
          "UMLS:C5201146",
          "icd11.foundation:382488319"
        ],
        "synonyms": [
          "BLAUS",
          "Blau syndrome",
          "EOS",
          "Jabs syndrome",
          "arthrocutaneouveal granulomatosis",
          "early-onset sarcoidosis",
          "granulomatosis, familial juvenile systemic",
          "granulomatosis, familial, Blau type",
          "granulomatous inflammatory arthritis, dermatitis, and uveitis, familial",
          "paediatric granulomatous arthritis",
          "pediatric granulomatous arthritis",
          "sarcoidosis, early-onset",
          "ACUG",
          "synovitis granulomatous with uveitis and cranial neuropathies",
          "synovitis, granulomatous, with uveitis and cranial neuropathies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Blau syndrome (BS) is a rare systemic inflammatory disease characterized by early onset granulomatous arthritis, uveitis and skin rash. BS now refers to both the familial and sporadic (formerly early-onset sarcoidosis) form of the same disease. The proposed term pediatric granulomatous arthritis is currently questioned since it fails to represent the systemic nature of the disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008523"
    },
    {
      "id": 20079,
      "label": "Löfgren syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025206",
          "MEDGEN:573580",
          "SCTID:238676008",
          "UMLS:C0340164"
        ],
        "synonyms": [
          "Loefgrens syndrome",
          "Löfgrens syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A sarcoidosis characterized by the triad of erythema nodosum, bilateral hilar lymphadenopathy on chest radiograph, and joint pain."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020666"
    },
    {
      "id": 23533,
      "label": "neurosarcoidosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799,
        19178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025938",
          "MEDGEN:97948",
          "MESH:C535814",
          "SCTID:230193008",
          "UMLS:C0393485",
          "icd11.foundation:1479285656"
        ],
        "synonyms": [
          "nervous system sarcoidosis",
          "neurosarcoidosis",
          "sarcoidosis of nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A sarcoidosis that involves the nervous system."
      },
      "child_count": 2,
      "reference_id": "MONDO:0045047"
    }
  ],
  "roots": [
    {
      "id": 19503,
      "label": "autoinflammatory syndrome"
    }
  ]
}