{
  "id": 19188,
  "label": "isolated spina bifida",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019351",
  "properties": {
    "xrefs": [
      "GARD:0007673",
      "MedDRA:10041524",
      "Orphanet:823"
    ],
    "synonyms": [
      "isolated spina bifida (disease)",
      "nonsyndromic spina bifida (disease)",
      "cleft spine",
      "open spine"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A spina bifida (disease) that is not part of a larger syndrome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 9741,
      "label": "spina bifida",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4427,
        4611,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080016",
          "EFO:0003105",
          "HP:0002414",
          "ICD10CM:Q05",
          "ICD10WHO:Q05",
          "ICD9:741",
          "MEDGEN:38283",
          "MESH:D016135",
          "NCIT:C101214",
          "SCTID:67531005",
          "UMLS:C0080178",
          "icd11.foundation:2036217905"
        ],
        "synonyms": [
          "rachischisis",
          "spina bifida",
          "spina bifida (disease)",
          "spinal meningocele",
          "spinal myelocele",
          "spinal myelomeningocele",
          "NTD",
          "neural tube defects, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A congenital neural tube defect in which vertebrae are not fully formed. It results in the protrusion of the spinal cord through the opening of the vertebrae."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008449"
    }
  ],
  "children": [
    {
      "id": 11682,
      "label": "neural tube defects, X-linked",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000669",
          "MEDGEN:337140",
          "MESH:C536359",
          "OMIM:301410",
          "UMLS:C1845026"
        ],
        "synonyms": [
          "neural tube defects, X-linked",
          "X-linked anencephaly/spina bifida",
          "anencephaly and spina bifida X-linked",
          "spina bifida, X-linked"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0010525"
    },
    {
      "id": 12244,
      "label": "neural tube defects, folate-sensitive",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024774",
          "MEDGEN:355746",
          "MESH:C536409",
          "OMIM:601634",
          "UMLS:C1866558"
        ],
        "synonyms": [
          "neural tube defects, folate-sensitive",
          "NTD, folate-sensitive",
          "NTDFS",
          "neural tube defects, folate-sensitive, susceptibility to",
          "neural tube defects, susceptibility to",
          "spina bifida, folate-sensitive"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011120"
    },
    {
      "id": 17442,
      "label": "spina bifida aperta",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020951",
          "MEDGEN:181490",
          "Orphanet:268369",
          "SCTID:58557008",
          "UMLS:C0917813",
          "icd11.foundation:187581000"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 7,
      "reference_id": "MONDO:0017062"
    },
    {
      "id": 17449,
      "label": "spina bifida cystica",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020958",
          "MEDGEN:21277",
          "MESH:D016137",
          "MedDRA:10071011",
          "NANDO:1200509",
          "NANDO:2100215",
          "NANDO:2200814",
          "NCIT:C101201",
          "Orphanet:268744",
          "UMLS:C0037917",
          "icd11.foundation:979482551"
        ],
        "synonyms": [
          "meningomyelocele",
          "myelomeningocele",
          "open spina bifida",
          "spina bifida aperta",
          "spina bifida manifesta",
          "spina bifida, open"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A congenital abnormality in which the spinal cord and meninges protrude through a defect in the spinal column. The protrusion is above the skin surface."
      },
      "child_count": 5,
      "reference_id": "MONDO:0017069"
    }
  ],
  "roots": [
    {
      "id": 9741,
      "label": "spina bifida"
    }
  ]
}