{
  "id": 19229,
  "label": "Isaac syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019399",
  "properties": {
    "xrefs": [
      "GARD:0006793",
      "MEDGEN:116151",
      "NANDO:1200510",
      "Orphanet:84142",
      "SCTID:305719002",
      "UMLS:C0242287",
      "icd11.foundation:646523932"
    ],
    "synonyms": [
      "Isaacs' syndrome",
      "Quantal squander syndrome",
      "acquired neuromyotonia",
      "continuous muscle fiber activity syndrome",
      "continuous muscle fibre activity syndrome",
      "neuromyotonia",
      "peripheral nerve hyperexcitability",
      "Isaac's-Merten's syndrome",
      "Isaac-Mertens syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Isaac's syndrome is an immune-mediated peripheral motor neuron disorder characterized by continuous muscle fiber activity at rest resulting in muscle stiffness, cramps, myokymia, and pseudomyotonia."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19001,
      "label": "muscular channelopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18957,
        29384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018917",
          "MEDGEN:1842600",
          "Orphanet:71864",
          "UMLS:C5681306"
        ],
        "synonyms": [
          "channelopathy of muscle tissue",
          "muscle tissue channelopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A channelopathy that involves the muscle tissue."
      },
      "child_count": 24,
      "reference_id": "MONDO:0019119"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19001,
      "label": "muscular channelopathy"
    }
  ]
}