{
  "id": 19261,
  "label": "systemic-onset juvenile idiopathic arthritis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019434",
  "properties": {
    "xrefs": [
      "EFO:1001999",
      "GARD:0010966",
      "MEDGEN:346934",
      "MESH:C565798",
      "NANDO:1200470",
      "NANDO:2201055",
      "NCIT:C119031",
      "Orphanet:85414",
      "SCTID:201796004",
      "UMLS:C1858558",
      "icd11.foundation:504387587"
    ],
    "synonyms": [
      "SoJIA",
      "Still disease",
      "sJIA",
      "systemic polyarthritis",
      "systemic-onset JIA",
      "Still's disease (formerly)",
      "systemic juvenile idiopathic arthritis",
      "systemic onset juvenile idiopathic arthritis",
      "systemic onset juvenile rheumatoid arthritis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 12534,
      "label": "juvenile idiopathic arthritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7203,
        7223,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:676",
          "EFO:0002609",
          "GARD:0018677",
          "ICD9:714.3",
          "ICD9:714.31",
          "ICD9:714.33",
          "MEDGEN:760659",
          "MESH:D001171",
          "MedDRA:10059177",
          "NANDO:1200469",
          "NANDO:2200415",
          "NCIT:C114357",
          "NORD:808",
          "OMIM:604302",
          "Orphanet:92",
          "SCTID:410502007",
          "UMLS:C3495559",
          "icd11.foundation:1322678686"
        ],
        "synonyms": [
          "Arthritis, Juvenile Rheumatoid",
          "JIA",
          "Juvenile idiopathic arthritis",
          "juvenile idiopathic arthritis",
          "juvenile rheumatoid arthritis",
          "rheumatoid arthritis, systemic juvenile, susceptibility to",
          "acute juvenile rheumatoid arthritis",
          "monarticular juvenile rheumatoid arthritis",
          "pauciarticular juvenile arthritis",
          "pauciarticular onset juvenile chronic arthritis",
          "systemic juvenile rheumatoid arthritis",
          "juvenile chronic arthritis",
          "juvenile chronic polyarthritis",
          "rheumatoid arthritis, systemic juvenile"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases)."
      },
      "child_count": 18,
      "reference_id": "MONDO:0011429"
    },
    {
      "id": 19503,
      "label": "autoinflammatory syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        7203
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051000",
          "ICD10CM:M04-M04",
          "MEDGEN:855741",
          "MedDRA:10072220",
          "NANDO:2100156",
          "NCIT:C119050",
          "Orphanet:93665",
          "UMLS:C3890737"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease."
      },
      "child_count": 74,
      "reference_id": "MONDO:0019751"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 12534,
      "label": "juvenile idiopathic arthritis"
    },
    {
      "id": 19503,
      "label": "autoinflammatory syndrome"
    }
  ]
}