{
  "id": 19264,
  "label": "enthesitis-related juvenile idiopathic arthritis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019437",
  "properties": {
    "xrefs": [
      "EFO:0009732",
      "GARD:0010969",
      "MEDGEN:854059",
      "NANDO:2201060",
      "NCIT:C119024",
      "Orphanet:85438",
      "SCTID:410801005",
      "UMLS:C3495919",
      "icd11.foundation:1128255226"
    ],
    "synonyms": [
      "ERA",
      "enthesitis-related JIA",
      "era",
      "enthesitis related arthritis, juvenile",
      "enthesitis-related arthritis",
      "juvenile enthesitis-related arthritis",
      "juvenile spondylarthropathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Enthesitis-related juvenile idiopathic arthritis is a subtype of juvenile idiopathic arthritis that is characterized by both arthritis and inflammation of an enthesitis site (the point at which a ligament, tendon, or joint capsule attaches to the bone). Signs and symptoms generally develop in late childhood or early adolescence and include pain, tenderness, and swelling in joints and at the enthesis. The knee and the back of the ankle (at the Achilles tendon) are the most commonly affected parts of the body. The underlying cause of enthesitis-related juvenile idiopathic arthritis is currently unknown (idiopathic). It is very rare for more than one member of a family to have juvenile arthritis; however, research suggests that having a family member with juvenile arthritis or any autoimmune disease may increase the risk of having juvenile arthritis, in general. Treatment usually involves different types of medications to help manage symptoms and/or physical therapy."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 12534,
      "label": "juvenile idiopathic arthritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7203,
        7223,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:676",
          "EFO:0002609",
          "GARD:0018677",
          "ICD9:714.3",
          "ICD9:714.31",
          "ICD9:714.33",
          "MEDGEN:760659",
          "MESH:D001171",
          "MedDRA:10059177",
          "NANDO:1200469",
          "NANDO:2200415",
          "NCIT:C114357",
          "NORD:808",
          "OMIM:604302",
          "Orphanet:92",
          "SCTID:410502007",
          "UMLS:C3495559",
          "icd11.foundation:1322678686"
        ],
        "synonyms": [
          "Arthritis, Juvenile Rheumatoid",
          "JIA",
          "Juvenile idiopathic arthritis",
          "juvenile idiopathic arthritis",
          "juvenile rheumatoid arthritis",
          "rheumatoid arthritis, systemic juvenile, susceptibility to",
          "acute juvenile rheumatoid arthritis",
          "monarticular juvenile rheumatoid arthritis",
          "pauciarticular juvenile arthritis",
          "pauciarticular onset juvenile chronic arthritis",
          "systemic juvenile rheumatoid arthritis",
          "juvenile chronic arthritis",
          "juvenile chronic polyarthritis",
          "rheumatoid arthritis, systemic juvenile"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases)."
      },
      "child_count": 18,
      "reference_id": "MONDO:0011429"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 12534,
      "label": "juvenile idiopathic arthritis"
    }
  ]
}