{
  "id": 19269,
  "label": "dextro-looped transposition of the great arteries",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019443",
  "properties": {
    "xrefs": [
      "DOID:0060770",
      "GARD:0005476",
      "MEDGEN:758887",
      "NANDO:1200698",
      "OMIMPS:608808",
      "Orphanet:860",
      "UMLS:C3531771"
    ],
    "synonyms": [
      "DTGA",
      "congenitally uncorrected transposition of the great arteries",
      "congenitally uncorrected transposition of the great vessels",
      "isolated ventriculoarterial discordance",
      "ventriculoarterial discordance with atrioventricular concordance"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Congenitally uncorrected transposition of the great arteries (congenitally uncorrected TGA), also referred to as complete transposition, is a congenital cardiac malformation characterized by atrioventricular concordance and ventriculoarterial (VA) discordance."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 2746,
      "label": "transposition of the great arteries",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19327
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007795",
          "MEDGEN:21245",
          "MESH:D014188",
          "NANDO:2200258",
          "NCIT:C84742",
          "Orphanet:216675",
          "UMLS:C0040761",
          "icd11.foundation:429190257"
        ],
        "synonyms": [
          "TGA",
          "TGV",
          "complete transposition",
          "great vessels transposition",
          "transposition of great vessels",
          "transposition of the great vessels"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A congenital cardiac defect in which two heart vessels are reversed (transposed)."
      },
      "child_count": 3,
      "reference_id": "MONDO:0000153"
    },
    {
      "id": 7116,
      "label": "congenital heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1682",
          "EFO:0005207",
          "ICD9:746.84",
          "ICD9:746.89",
          "ICD9:746.9",
          "MEDGEN:57501",
          "MESH:D006330",
          "NCIT:C95834",
          "SCTID:13213009",
          "UMLS:C0152021",
          "icd11.foundation:2004408087"
        ],
        "synonyms": [
          "heart malformation",
          "congenital anomaly of heart",
          "congenital heart defect",
          "congenital heart defects",
          "Abnormality, heart",
          "abnormalities, heart",
          "defect, congenital heart",
          "defects, congenital heart",
          "heart abnormalities",
          "heart abnormality",
          "heart defect, congenital",
          "heart, malformation Of"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart disease that is present at birth. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot, and patent foramen ovale."
      },
      "child_count": 46,
      "reference_id": "MONDO:0005453"
    },
    {
      "id": 24272,
      "label": "cardiogenetic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6967
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "hereditary heart disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions, with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology that are characterized by abnormalities in the cardiovascular system."
      },
      "child_count": 146,
      "reference_id": "MONDO:0100547"
    }
  ],
  "children": [
    {
      "id": 14494,
      "label": "congenital heart defects, multiple types, 6",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2732,
        19269
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060772",
          "GARD:0024928",
          "MEDGEN:462571",
          "OMIM:613854",
          "UMLS:C3151221"
        ],
        "synonyms": [
          "DTGA3",
          "GDF1 dextro-looped transposition of the great arteries",
          "congenital heart defects, multiple types, 6",
          "dextro-looped transposition of the great arteries caused by mutation in GDF1",
          "dextro-looped transposition of the great arteries type 3",
          "transposition of the great arteries, dextro-looped type 3",
          "CHTD6",
          "transposition of the great arteries, dextro-looped 3",
          "transposition of the great arteries, dextro-looped 3, formerly"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any dextro-looped transposition of the great arteries in which the cause of the disease is a mutation in the GDF1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013463"
    },
    {
      "id": 16857,
      "label": "isolated congenitally uncorrected transposition of the great arteries",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19269
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020502",
          "MEDGEN:1842921",
          "Orphanet:216718",
          "UMLS:C5679810"
        ],
        "synonyms": [
          "isolated congenitally uncorrected transposition of the great vessels"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0016302"
    },
    {
      "id": 16858,
      "label": "congenitally uncorrected transposition of the great arteries with cardiac malformation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19269
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020503",
          "MEDGEN:1843053",
          "NANDO:1200701",
          "Orphanet:216729",
          "UMLS:C5679811"
        ],
        "synonyms": [
          "TGA with cardiac malformation",
          "congenitally uncorrected transposition of the great vessels with cardiac malformation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0016303"
    },
    {
      "id": 19845,
      "label": "congenitally uncorrected transposition of the great arteries with coarctation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19269
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019614",
          "MEDGEN:1842891",
          "NANDO:1200703",
          "Orphanet:99042",
          "UMLS:C5680321"
        ],
        "synonyms": [
          "TGA with coarctation",
          "congenitally uncorrected transposition of the great vessels with coarctation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020385"
    }
  ],
  "roots": [
    {
      "id": 2746,
      "label": "transposition of the great arteries"
    },
    {
      "id": 7116,
      "label": "congenital heart disease"
    },
    {
      "id": 24272,
      "label": "cardiogenetic disease"
    }
  ]
}