{
  "id": 19296,
  "label": "adult T-cell leukemia/lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019471",
  "properties": {
    "xrefs": [
      "DOID:0050523",
      "GARD:0019076",
      "ICD9:204.80",
      "ICDO:9827/3",
      "MEDGEN:44128",
      "MedDRA:10001413",
      "NCIT:C3184",
      "ONCOTREE:ATLL",
      "Orphanet:86875",
      "SCTID:110007008",
      "UMLS:C0023493",
      "icd11.foundation:430573082"
    ],
    "synonyms": [
      "ATLL",
      "T-cell leukaemia of adults",
      "T-cell leukemia of adults",
      "adult T-cell leukaemia",
      "adult T-cell leukemia",
      "adult T-cell leukemia/lymphoma",
      "HTLV-1 associated adult T-cell lymphoma/leukemia",
      "HTLV-I associated adult T-cell leukemia/lymphoma",
      "adult T cell lymphoma/leukemia",
      "adult T-cell leukemia/lymphoma (HTLV-1 positive)",
      "adult T-cell lymphoma",
      "adult T-cell lymphoma/leukemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A peripheral (mature) T-cell neoplasm linked to the human T-cell leukemia virus type 1 (HTLV-1), adult T-cell leukemia/lymphoma is endemic in several regions of the world, in particular Japan, the Caribbean, and parts of Central Africa."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5547,
      "label": "adult lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5825",
          "GARD:0023607",
          "MEDGEN:233965",
          "NANDO:2100004",
          "NCIT:C7587",
          "UMLS:C1332206"
        ],
        "synonyms": [
          "lymphoma",
          "adult lymphoma",
          "lymphoma of adults"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that occurs in an adult."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003660"
    },
    {
      "id": 7179,
      "label": "T-cell leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6569,
        7079
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:715",
          "EFO:0005592",
          "GARD:0024203",
          "MEDGEN:6064",
          "MESH:D015458",
          "UMLS:C0023492"
        ],
        "synonyms": [
          "T cell leukaemia (disease)",
          "T cell leukemia (disease)",
          "leukaemia (disease) of T cell",
          "leukemia (disease) of T cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant disease of the T-lymphocytes in the bone marrow, thymus, and/or blood."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005525"
    },
    {
      "id": 7417,
      "label": "human T-lymphotropic virus 1 infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007316",
          "GARD:0009645",
          "MEDGEN:6919",
          "MESH:D015490",
          "UMLS:C0020097"
        ],
        "synonyms": [
          "Human T-lymphotropic virus 1 caused disease or disorder",
          "Human T-lymphotropic virus 1 disease or disorder",
          "Human T-lymphotropic virus 1 infectious disease",
          "human T-lymphotropic virus 1 infectious disease",
          "HTLV-1",
          "Human T lymphotropic virus type 1"
        ],
        "definition": "A viral infectious disease that results in increased proliferation of affected CD4 lymphocytes, has material basis in Human T-lymphotropic virus 1, which is transmitted by sexual contact, transmitted by contaminated needles used by intravenous-drug users, and transmitted by breast feeding. The person infected with HTLV-1 eventually develop an often rapidly fatal leukemia, while others will develop a debilitative myelopathy, uveitis, infectious dermatitis, or another inflammatory disorder."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005801"
    },
    {
      "id": 16517,
      "label": "T-cell non-Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18836
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081312",
          "GARD:0020133",
          "ICD9:202.70",
          "MEDGEN:86957",
          "MESH:D016399",
          "MedDRA:10042971",
          "NCIT:C3466",
          "Orphanet:171918",
          "SCTID:109978004",
          "UMLS:C0079772"
        ],
        "synonyms": [
          "T cell lymphoma",
          "T-cell NHL",
          "T-cell and NK-cell non-Hodgkin lymphoma",
          "T-cell and NK-cell non-Hodgkin's lymphoma",
          "T-cell lymphoma",
          "T-cell non-Hodgkin lymphoma",
          "T-cell non-Hodgkin's lymphoma",
          "non-Hodgkin's T-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003"
      },
      "child_count": 9,
      "reference_id": "MONDO:0015760"
    },
    {
      "id": 17658,
      "label": "virus associated tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        20721
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1842723",
          "Orphanet:289635",
          "UMLS:C5681008"
        ]
      },
      "child_count": 16,
      "reference_id": "MONDO:0017341"
    },
    {
      "id": 20413,
      "label": "deltaretrovirus infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001303",
          "MEDGEN:9320",
          "MESH:D006800",
          "UMLS:C0020091"
        ],
        "synonyms": [
          "BLV infection",
          "BLV infections",
          "Deltaretrovirus infection",
          "HTLV BLV infections",
          "HTLV infection",
          "HTLV infections",
          "HTLV-BLV infection",
          "HTLV-BLV infections",
          "infection, Deltaretrovirus",
          "infections, Deltaretrovirus"
        ],
        "definition": "Infections caused by the HTLV or BLV deltaretroviruses. They include human T-cell leukemia-lymphoma (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021184"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5547,
      "label": "adult lymphoma"
    },
    {
      "id": 7179,
      "label": "T-cell leukemia"
    },
    {
      "id": 7417,
      "label": "human T-lymphotropic virus 1 infectious disease"
    },
    {
      "id": 16517,
      "label": "T-cell non-Hodgkin lymphoma"
    },
    {
      "id": 17658,
      "label": "virus associated tumor"
    },
    {
      "id": 20413,
      "label": "deltaretrovirus infections"
    }
  ]
}