{
  "id": 19298,
  "label": "enteropathy-associated T-cell lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019473",
  "properties": {
    "xrefs": [
      "GARD:0009809",
      "ICD10CM:C86.2",
      "ICD9:202.70",
      "ICDO:9717/3",
      "MEDGEN:96832",
      "MESH:D058527",
      "MedDRA:10022703",
      "NCIT:C4737",
      "ONCOTREE:EATL",
      "Orphanet:86880",
      "SCTID:277654008",
      "UMLS:C0456889",
      "icd11.foundation:958629729"
    ],
    "synonyms": [
      "EATL",
      "EATL, type I",
      "ETTL",
      "enteropathy associated T-cell lymphoma",
      "enteropathy-associated T-cell lymphoma, type I",
      "enteropathy-type T-cell lymphoma",
      "intestinal T-cell lymphoma",
      "EATCL",
      "high-grade pleomorphic peripheral T-cell lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An uncommon mature T-cell lymphoma of intraepithelial lymphocytes. It usually arises from the small intestine, most commonly the jejunum or ileum. Other less frequent primary anatomic sites include the duodenum, stomach, colon, or outside the gastrointestinal tract. It is seen with increased frequency in regions with a high prevalence of celiac disease."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 16517,
      "label": "T-cell non-Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18836
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081312",
          "GARD:0020133",
          "ICD9:202.70",
          "MEDGEN:86957",
          "MESH:D016399",
          "MedDRA:10042971",
          "NCIT:C3466",
          "Orphanet:171918",
          "SCTID:109978004",
          "UMLS:C0079772"
        ],
        "synonyms": [
          "T cell lymphoma",
          "T-cell NHL",
          "T-cell and NK-cell non-Hodgkin lymphoma",
          "T-cell and NK-cell non-Hodgkin's lymphoma",
          "T-cell lymphoma",
          "T-cell non-Hodgkin lymphoma",
          "T-cell non-Hodgkin's lymphoma",
          "non-Hodgkin's T-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003"
      },
      "child_count": 9,
      "reference_id": "MONDO:0015760"
    }
  ],
  "children": [
    {
      "id": 7935,
      "label": "small intestinal enteropathy-associated T-cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3028,
        4030,
        6569,
        19298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000535",
          "GARD:0024406",
          "MEDGEN:275445",
          "NCIT:C39610",
          "UMLS:C1519371"
        ],
        "synonyms": [
          "enteropathy-associated T-cell lymphoma of small intestine",
          "small intestinal EATL",
          "small intestinal enteropathy-type T-cell lymphoma",
          "small intestine enteropathy-associated T-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An enteropathy-associated T-cell lymphoma arising from the small intestine, most commonly the jejunum or ileum. Patients usually present with abdominal pain, often associated with intestinal perforation. There is often a history of celiac disease. The lymphoma cells are usually medium-sized to large and form an ulcerating mucosal lesion with invasion of the small intestinal wall. Villous atrophy is present in the adjacent small intestinal mucosa. In a minority of cases the lymphoma cells are medium-sized and form a monomorphic infiltrate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006418"
    }
  ],
  "roots": [
    {
      "id": 16517,
      "label": "T-cell non-Hodgkin lymphoma"
    }
  ]
}