{
  "id": 19303,
  "label": "histiocytic sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019479",
  "properties": {
    "xrefs": [
      "DOID:0080915",
      "GARD:0019080",
      "ICD10CM:C96.A",
      "ICD9:171.9",
      "ICDO:9755/3",
      "MEDGEN:137793",
      "MESH:D054747",
      "NCIT:C27349",
      "ONCOTREE:HS",
      "Orphanet:86896",
      "SCTID:109988003",
      "UMLS:C0334663",
      "icd11.foundation:1925254893",
      "icd11.foundation:911785965"
    ],
    "synonyms": [
      "histiocytic sarcoma",
      "sarcoma, histiocytic, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An aggressive malignant neoplasm with a poor response to therapy, usually presenting as stage III/IV disease. It is characterized by the presence of neoplastic cells with morphologic and immunophenotypic characteristics similar to those seen in mature histiocytes."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7797,
      "label": "histiocytic and dendritic cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16514,
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5621",
          "EFO:1000297",
          "GARD:0019441",
          "MEDGEN:714988",
          "NCIT:C9294",
          "Orphanet:98287",
          "UMLS:C1292762"
        ],
        "synonyms": [
          "histiocytic and Dendritic cell neoplasms",
          "histiocytic and Dendritic cell tumors",
          "histiocytic and Dendritic cell tumours",
          "histiocytic and dendritic cell neoplasm",
          "histiocytic and dendritic cell",
          "histiocytic and dendritic cell cancer",
          "histiocytic and dendritic cell tumor",
          "histiocytic and dendritic cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Rare tumors that affect the hematopoietic and lymphoid tissues. The cells of origin are the histiocytes and accessory cells. They can occur at any age and show no significant variations in geographical distribution. This category includes the histiocytic sarcoma, Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitading dendritic cell sarcoma/tumor, follicular dendritic cell sarcoma/tumor, and dendritic cell sarcoma, not otherwise specified. (WHO, 2001)"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006247"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7797,
      "label": "histiocytic and dendritic cell neoplasm"
    }
  ]
}