{
  "id": 19326,
  "label": "cutaneous leukocytoclastic angiitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019509",
  "properties": {
    "xrefs": [
      "GARD:0007851",
      "MEDGEN:881641",
      "NCIT:C122919",
      "Orphanet:889",
      "SCTID:718217000",
      "UMLS:C4049638",
      "icd11.foundation:247535295",
      "icd11.foundation:71458216"
    ],
    "synonyms": [
      "cutaneous hypersensitivity vasculitis",
      "cutaneous leukocytoclastic vasculitis",
      "cutaneous small vessel vasculitis",
      "cutaneous small-vessel vasculitis",
      "hypersensitivity angiitis",
      "leukocytoclastic angiitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Cutaneous leukocytoclastic angiitis is a small-vessel vasculitis presenting with palpable purpura and urticarial lesions which predate the purpuric lesions most frequently observed on the legs. Systemic symptoms including fever, cough, hemoptysis, sinusitis, arthralgia, arthritis, myalgia, abdominal pain, diarrhea, hematochezia, paresthesia, weakness, and hematuria may be observed. Skin biopsy reveals exudates rich in neutrophils, endothelial damage, fibrin deposition, and leukocytoclasis in postcapillary venules of small vessels. Cutaneous leukocytoclastic angiitis can be idiopathic (in up to 50% of cases) or secondary to infections, medications (such as antituberculosis medication), collagen vascular diseases, or neoplasms."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18813
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019984",
          "MEDGEN:1842565",
          "Orphanet:156149",
          "UMLS:C5680655"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0015491"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis"
    }
  ]
}