{
  "id": 19335,
  "label": "tetrasomy X",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019525",
  "properties": {
    "xrefs": [
      "GARD:0007754",
      "ICD9:758.81",
      "MEDGEN:120544",
      "MESH:C536502",
      "Orphanet:9",
      "SCTID:10567003",
      "UMLS:C0265496",
      "icd11.foundation:1181464236"
    ],
    "synonyms": [
      "48,XXXX syndrome",
      "quadruple X",
      "tetra X",
      "tetrasomy type X",
      "48 XXXX",
      "48 XXXX syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Tetrasomy X is a sex chromosome anomaly caused by the presence of two extra X chromosomes in females (48,XXXX instead of 46,XX)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7067,
        16330,
        20362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019294",
          "MEDGEN:443920",
          "OMIMPS:311360",
          "Orphanet:95710",
          "UMLS:C2930861"
        ],
        "synonyms": [
          "hereditary primary ovarian failure",
          "inherited POI",
          "inherited premature ovarian failure",
          "inherited primary ovarian insufficiency",
          "non-acquired premature ovarian failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 164,
      "reference_id": "MONDO:0019852"
    },
    {
      "id": 21951,
      "label": "tetrasomy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90710",
          "MESH:D058670",
          "NCIT:C36601",
          "UMLS:C0333689"
        ],
        "definition": "A chromosomal disorder consisting of the presence of two chromosomes of the same type in addition to the normal diploid number."
      },
      "child_count": 4,
      "reference_id": "MONDO:0030502"
    },
    {
      "id": 24425,
      "label": "chromosome X disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19717
      ],
      "type_id": 0,
      "properties": {
        "definition": "Chromosomal disorder in which chromosome X is affected."
      },
      "child_count": 13,
      "reference_id": "MONDO:0700027"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19578,
      "label": "inherited primary ovarian failure"
    },
    {
      "id": 21951,
      "label": "tetrasomy"
    },
    {
      "id": 24425,
      "label": "chromosome X disorder"
    }
  ]
}