{
  "id": 19341,
  "label": "hemolytic anemia due to glutathione reductase deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019531",
  "properties": {
    "xrefs": [
      "DOID:0051009",
      "GARD:0016784",
      "MEDGEN:1684855",
      "OMIM:618660",
      "Orphanet:90030",
      "UMLS:C5231513"
    ],
    "synonyms": [
      "hemolytic anemia due to glutathione reductase deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Haemolytic anemia due to glutathione reductase (GSR) deficiency is characterized by nearly complete absence of GSR activity in erythrocytes."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7998,
      "label": "congenital nonspherocytic hemolytic anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3000,
        5573,
        18953
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2861",
          "EFO:1000641",
          "GARD:0024433",
          "ICD9:282.3",
          "MEDGEN:284",
          "MESH:D000746",
          "OMIMPS:300908",
          "SCTID:301317008",
          "UMLS:C0002882"
        ],
        "synonyms": [
          "anemia, congenital, nonspherocytic hemolytic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. Common causes include deficiencies in glucose-6-phosphate isomerase; pyruvate kinase; and glucose-6-phosphate dehydrogenase."
      },
      "child_count": 30,
      "reference_id": "MONDO:0006506"
    },
    {
      "id": 22996,
      "label": "inherited glutathione metabolism disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19105,
        23664,
        24199
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025825",
          "MEDGEN:541346",
          "SCTID:72262000",
          "UMLS:C0268518"
        ],
        "synonyms": [
          "disorder of glutathione metabolism",
          "glutathione metabolism disorder, inherited",
          "inborn error of glutathione metabolic process",
          "inborn error of glutathione metabolism",
          "inborn glutathione metabolic process disorder",
          "rare inborn error of glutathione metabolic process"
        ],
        "definition": "An inherited metabolic disease that is has its basis in the disruption of glutathione metabolic process."
      },
      "child_count": 18,
      "reference_id": "MONDO:0040566"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7998,
      "label": "congenital nonspherocytic hemolytic anemia"
    },
    {
      "id": 22996,
      "label": "inherited glutathione metabolism disease"
    }
  ]
}