{
  "id": 19346,
  "label": "Shiga toxin-associated hemolytic uremic syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019536",
  "properties": {
    "xrefs": [
      "GARD:0006588",
      "MEDGEN:383843",
      "NANDO:2200640",
      "Orphanet:90038",
      "UMLS:C1856143"
    ],
    "synonyms": [
      "D+HUS",
      "STEC Hemolytic Uremic Syndrome",
      "Shiga-like toxin-associated HUS",
      "Sxt-HUS",
      "hemolytic-uremic syndrome with diarrhea",
      "hemolytic-uremic syndrome with diarrhoea",
      "typical HUS",
      "typical hemolytic-uremic syndrome",
      "D-plus hemolytic uremic syndrome (D+HUS)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A rare thrombotic microangiopathy characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction that is usually associated with prodromal enteritis caused by Shigella dysentriae type 1 or E. Coli."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5550,
      "label": "hemolytic anemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5966
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:583",
          "GARD:0023610",
          "ICD10CM:D55-D59",
          "MEDGEN:1916",
          "MESH:D000743",
          "NANDO:2200636",
          "NCIT:C34376",
          "SCTID:61261009",
          "UMLS:C0002878"
        ],
        "synonyms": [
          "anaemia hemolytic",
          "anemia hemolytic",
          "anemia, hemolytic",
          "hemolytic anemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Anemia resulting from the premature destruction of the peripheral blood red cells. It may be congenital or it may be caused by infections, medications, or malignancies."
      },
      "child_count": 11,
      "reference_id": "MONDO:0003664"
    },
    {
      "id": 22768,
      "label": "infection-related hemolytic uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3755,
        20718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022234",
          "MEDGEN:1826072",
          "Orphanet:544482",
          "UMLS:C5680165"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0034103"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5550,
      "label": "hemolytic anemia"
    },
    {
      "id": 22768,
      "label": "infection-related hemolytic uremic syndrome"
    }
  ]
}