{
  "id": 19369,
  "label": "localized scleroderma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019562",
  "properties": {
    "xrefs": [
      "DOID:8472",
      "EFO:1001361",
      "GARD:0007058",
      "ICD10CM:L94.0",
      "ICD9:701.0",
      "MEDGEN:48586",
      "MESH:D012594",
      "MedDRA:10039712",
      "NCIT:C72069",
      "Orphanet:90289",
      "SCTID:201048007",
      "UMLS:C0036420",
      "icd11.foundation:1430740369"
    ],
    "synonyms": [
      "circumscribed scleroderma",
      "localised fibrosing scleroderma",
      "localised scleroderma (disorder) [ambiguous]",
      "localized fibrosing scleroderma",
      "localized morphoea",
      "localized scleroderma",
      "localized scleroderma (disorder) [ambiguous]",
      "morphea",
      "Scleroderma, localised",
      "Scleroderma, localized"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Localized scleroderma is the skin localized form of scleroderma characterized by fibrosis of the skin causing cutaneous plaques or strips."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 19180,
      "label": "scleroderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7203,
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:419",
          "EFO:1001993",
          "GARD:0018705",
          "HP:0100324",
          "MEDGEN:3770",
          "MedDRA:10039710",
          "NCIT:C26746",
          "Orphanet:801",
          "UMLS:C0011644"
        ],
        "synonyms": [
          "scleroderma",
          "scleroderma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0019340"
    }
  ],
  "children": [
    {
      "id": 21255,
      "label": "lipodermatosclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4496,
        8067,
        19369
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009671",
          "MEDGEN:140802",
          "MESH:C537026",
          "SCTID:410016009",
          "UMLS:C0406500",
          "icd11.foundation:473315619"
        ],
        "synonyms": [
          "acute lipodermatosclerosis",
          "hypodermitis sclerodermaformis",
          "sclerosing panniculitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Lipodermatosclerosis refers to changes in the skin of the lower legs. It is a form of panniculitis (inflammation of the layer of fat under the skin). Signs and symptoms include pain, hardening of skin, change in skin color (redness), swelling, and a tapering of the legs above the ankles. The exact underlying cause is unknown; however, it appears to be associated with venous insufficiency and/or obesity. Treatment usually includes compression therapy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023646"
    },
    {
      "id": 23186,
      "label": "linear scleroderma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19369
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009513",
          "ICD10CM:L94.1",
          "MEDGEN:75518",
          "NCIT:C116780",
          "SCTID:22784002",
          "UMLS:C0263409"
        ],
        "synonyms": [
          "linear Scleroderma",
          "linear scleroderma",
          "Scleroderma, linear",
          "en coup de saber",
          "en coup de sabre",
          "linear morphea"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A type of localized scleroderma characterized by a long strip of indurated skin, which is typically found unilaterally on an arm or leg, and sometimes on the forehead or trunk. This disorder often affects the tissues beneath the skin, causing damage to bones, muscle or other organs. It can limit movement, alter growth, and disfigure the affected area."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043294"
    }
  ],
  "roots": [
    {
      "id": 19180,
      "label": "scleroderma"
    }
  ]
}