{
  "id": 19390,
  "label": "scleromyxedema without monoclonal gammopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019585",
  "properties": {
    "xrefs": [
      "GARD:0019144",
      "MEDGEN:1843341",
      "Orphanet:90400",
      "UMLS:C5681463"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Scleromyxedema without monoclonal gammopathy is a form of atypical lichen myxedematosus, characterized by a generalized sclerodermoid infiltration of skin studded with multiple, firm papules of 1-3 mm in diameter involving face (leonine appearance), trunk, and limbs, without monoclonal gammopathy. The involvement of the face can be missing and pruritus may be prominent."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19273,
      "label": "atypical lichen myxedematosus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18480
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019066",
          "MEDGEN:1383234",
          "Orphanet:86797",
          "SCTID:725148000",
          "UMLS:C4510874"
        ],
        "synonyms": [
          "Intermediate lichen myxedematosus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Atypical lichen myxedematosus is an intermediate form of lichen myxedematosus (LM) (a form of mucin dermal deposit) which does not meet the criteria for either scleromyxedema or the localized form. Three clinical subtypes have been described and include scleromyxedema without monoclonal gammopathy; localized forms with monoclonal gammopathy and/or systemic symptoms; localized forms with mixed features of the 5 subtypes of localized LM (discrete form, acral persistent papular mucinosis, self-healing papular mucinosis, papular mucinosis of infancy, and a pure nodular form). The course of atypical LM is unpredictable because only a few cases have been reported."
      },
      "child_count": 3,
      "reference_id": "MONDO:0019447"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19273,
      "label": "atypical lichen myxedematosus"
    }
  ]
}