{
  "id": 19427,
  "label": "renal hypoplasia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019637",
  "properties": {
    "xrefs": [
      "DOID:0080204",
      "GARD:0019172",
      "HP:0000089",
      "MEDGEN:120571",
      "MedDRA:10049102",
      "NANDO:2200155",
      "Orphanet:93101",
      "SCTID:32659003",
      "UMLS:C0266295"
    ],
    "synonyms": [
      "renal hypoplasia",
      "renal hypoplasia (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Renal hypoplasia is a developmental anomaly in which one or both kidneys (unilateral or bilateral renal hypoplasia, respectively) have a deficit in the number of nephrons and may be small. Oligomeganephronia represents a severe variant of hypoplasia in which nephron number is reduced by 80% and nephrons are markedly hypertrophied."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6948,
      "label": "kidney disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4253
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:557",
          "EFO:0003086",
          "ICD9:583.81",
          "MEDGEN:9635",
          "MESH:D007674",
          "NCIT:C3149",
          "SCTID:90708001",
          "UMLS:C0022658"
        ],
        "synonyms": [
          "disease of kidney",
          "disease or disorder of kidney",
          "disorder of kidney",
          "kidney disease",
          "kidney disease or disorder",
          "kidney disorder",
          "renal disease",
          "renal disorder",
          "nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the kidney."
      },
      "child_count": 57,
      "reference_id": "MONDO:0005240"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q00-Q99",
          "MEDGEN:1843482",
          "UMLS:C0694457"
        ],
        "definition": "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development."
      },
      "child_count": 190,
      "reference_id": "MONDO:0021147"
    }
  ],
  "children": [
    {
      "id": 19690,
      "label": "renal hypoplasia, unilateral",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019373",
          "ICD10CM:Q60.3",
          "MEDGEN:609098",
          "Orphanet:97361",
          "UMLS:C0431691"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Unilateral renal hypoplasia is a form of renal hypoplasia, a renal developmental anomaly in which one kidney is small and has a deficit in the number of nephrons present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019979"
    },
    {
      "id": 19691,
      "label": "renal hypoplasia, bilateral",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19427
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019374",
          "ICD10CM:Q60.4",
          "MEDGEN:609099",
          "Orphanet:97362",
          "SCTID:268232000",
          "UMLS:C0431692"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Bilateral renal hypoplasia is a form of renal hypoplasia, a renal developmental anomaly in which both kidneys are small and have a deficit in the number of nephrons present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019980"
    }
  ],
  "roots": [
    {
      "id": 6948,
      "label": "kidney disorder"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis"
    }
  ]
}