{
  "id": 19484,
  "label": "type II mixed cryoglobulinemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0019726",
  "properties": {
    "xrefs": [
      "GARD:0019220",
      "MEDGEN:1842376",
      "Orphanet:93554",
      "UMLS:C5680264"
    ],
    "synonyms": [
      "MC type II"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Type II mixed cryoglobulinemia, a relatively rare clinico-serological subtype of mixed cryoglobulinemia (MC), is an immune complex disorder characterized by purpura, weakness and arthralgia and defined immunochemically by cryoglobulins composed of polyclonal IgGs (autoantigens) and monoclonal IgM (autoantibody)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8798,
      "label": "Cryoglobulinemic vasculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16323
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006386",
          "ICD9:273.2",
          "MEDGEN:343814",
          "MESH:C565141",
          "MedDRA:10027756",
          "NORD:1452",
          "OMIM:123550",
          "Orphanet:91138",
          "SCTID:190815001",
          "UMLS:C1852456",
          "icd11.foundation:55133785"
        ],
        "synonyms": [
          "MC",
          "Mixed Cryoglobulinemia",
          "essential cryoglobulinemia",
          "essential mixed cryoglobulinemia",
          "mixed cryoglobulinemia",
          "primary cryoglobulinemia",
          "Meltzer syndrome",
          "cryoglobulinemia, familial mixed",
          "familial mixed cryoglobulinemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Mixed cryoglobulinemia (MC) is a rare multisystem disease characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifested clinically by a classical triad of purpura, weakness and arthralgia."
      },
      "child_count": 2,
      "reference_id": "MONDO:0007407"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8798,
      "label": "Cryoglobulinemic vasculitis"
    }
  ]
}